10 citations
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October 2010 in “Hepatology” Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.
April 2018 in “Journal of Investigative Dermatology” Fetuin A may increase collagen production and promote scarring.
January 2025 in “Biochemical Pharmacology” Peficitinib can turn human fibroblasts into cells that help grow hair.
14 citations
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April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
2 citations
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March 2015 in “Hepatitis Monthly” A woman's hair loss during Hepatitis C treatment with PEG-INF-a-2a and Ribavirin was reversible after stopping the medication.
March 2013 in “Revista Brasileira de Cirurgia Plástica” Using platelet growth factors can improve hair density in transplants, especially for those with fine hair.
30 citations
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July 1998 in “British Journal of Dermatology” Fat cells slow hair cell growth but speed up their development.
December 2025 in “JEADV Clinical Practice” A woman with hair loss condition experienced rare hair color return, suggesting it might help diagnose the condition.
2 citations
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April 2017 in “Actas Dermo-Sifiliográficas” Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.
August 2014 in “Journal of clinical & experimental dermatology research” Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
21 citations
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July 2024 in “Journal of Investigative Dermatology”
6 citations
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January 2019 in “The American Journal of Dermatopathology” The conclusion is that fat tissue in the skin is a new finding in Frontal fibrosing alopecia and may contribute to hair follicle and muscle degeneration.
127 citations
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July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
Compound 6 is a promising candidate for better wound healing.
The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.
1235 citations
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December 2013 in “Nature” Two fibroblast types shape skin structure and repair differently.
1 citations
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March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Biodegradable scaffolds help regenerate wounds and hair by activating the immune system.
36 citations
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March 2011 in “Nature Communications” Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
4 citations
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June 2022 in “Journal of Cosmetic Dermatology” Multi-peptide factors from fibroblasts may stimulate hair growth by increasing growth factors and β-catenin in hair cells.
23 citations
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January 2012 in “International Food Research Journal” Tofacitinib effectively treated a woman's severe symptoms from a rare autoimmune condition.
37 citations
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September 2008 in “The American journal of surgical pathology” Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."
Some fibroblast growth factors may promote hair growth similarly to minoxidil and could potentially treat hair loss.
June 2025 in “Dermatologic Surgery” GFC improves hair quickly, while PRP offers longer-lasting benefits; using both sequentially is recommended.
IL-1 and IL-7 help activate cells that boost hair follicle stem cell growth, aiding wound healing.
7 citations
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March 2023 in “The Journal of Biochemistry” LONRF1 is important for oxidative damage response and tissue remodeling during wound healing.
5 citations
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January 2016 in “Skin appendage disorders” Frontal fibrosing alopecia might be linked to autoimmune diseases.
January 2016 in “Indian dermatology online journal” Frontal fibrosing alopecia causes hair loss at the front hairline, and no effective treatment exists.
328 citations
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November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
3 citations
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September 2017 in “Stem cell investigation” PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.