418 citations
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January 2018 in “Journal of Investigative Dermatology” Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
299 citations
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January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
113 citations
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June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
66 citations
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May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
44 citations
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August 2008 in “Archives of Dermatology” Trichoscopy is a non-invasive way to diagnose hair and scalp problems without needing hair samples.
32 citations
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October 2004 in “Experimental Dermatology” α-MSH may help treat skin inflammation and fibrosis.
31 citations
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December 2016 in “Anais Brasileiros de Dermatologia” DHEA reduction may be linked to frontal fibrosing alopecia, but more research is needed.
28 citations
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October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
26 citations
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July 2006 in “International Journal of Cosmetic Science” Taurine helps protect and promote hair growth.
18 citations
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January 2022 in “Oxidative Medicine and Cellular Longevity” Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
13 citations
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January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
13 citations
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February 2017 in “Science” Turning scar-forming cells into fat cells can reduce scarring.
11 citations
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August 2023 in “Burns” Nerve growth factor helps improve healing time and scar quality in burn wounds.
10 citations
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January 2015 in “International Journal of Trichology” Mechanical stress contributes to hair loss in androgenetic alopecia.
9 citations
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November 2004 in “SKINmed Dermatology for the Clinician” A man with hair loss developed a condition causing scarring and inflammation in both bald and non-bald areas of his scalp.
4 citations
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July 1994 in “Clinics in Dermatology” Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.
2 citations
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August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The Aligned membranes improved wound healing and hair growth with a better immune response in mice.
1 citations
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January 2024 in “International journal of molecular sciences” TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
1 citations
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November 2018 in “Journal of pathology and translational medicine” Fetal death was caused by umbilical cord stricture with hair growth in the Wharton jelly.
1 citations
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September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
1 citations
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January 2007 in “The Internet Journal of Dermatology” A rare, harmless skin tumor was found on a man's nose.
Advances in RNA research and skin models offer hope for better skin healing without scarring.
April 2026 in “International Journal of Molecular Sciences” Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.
April 2026 in “Research Square” E13 fetal mouse fibroblast vesicles may help reduce scarring.
April 2026 in “Journal of Investigative Dermatology” Mechanotransduction aids healthy wound healing by promoting specific fibroblasts.
Fraser's Dolphin can heal skin wounds with minimal scarring, unlike humans.
March 2026 in “Wound Repair and Regeneration” MARCKSL1 is important for wound healing and could be a target to reduce scarring.
July 2025 in “Journal of Investigative Dermatology” Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.
July 2025 in “International Journal of Molecular Sciences” Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
Correcting EDA fibronectin organization and YAP translocation can improve wound healing in fibrotic conditions.