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April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
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November 2020 The Wnt1/βcatenin pathway is crucial for heart repair after injury.
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October 2017 in “Circulation” A new technology showed that the SOX9 gene might control heart scar formation after injury, suggesting new treatment possibilities.
April 2026 in “Brazilian Journal of Hair Health” Perifollicular fibrosis hinders hair regrowth in androgenetic alopecia, and new treatments targeting fibrosis are needed.
April 2026 in “Journal of Investigative Dermatology” Mechanotransduction aids healthy wound healing by promoting specific fibroblasts.
Adipocytes in atopic dermatitis skin change and worsen inflammation and fibrosis.
November 2025 in “Journal of Clinical Medicine” PRP may help reduce scar symptoms like pain and itching after six months.
Accurate diagnosis is crucial for effective treatment of similar hair loss conditions.
July 2025 in “Journal of Investigative Dermatology” Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.
Human dermal papilla cell vesicles can reduce skin fibrosis in mice.
January 2025 in “Dermatologic Therapy” CO₂ laser therapy improves skin and hair growth in localized scleroderma without severe side effects.
COVID-19 pneumonia may cause lasting lung damage like fibrosis.
September 2024 in “JAMA Dermatology” Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.
June 2024 in “Current Developments in Nutrition” KeraGLO improves skin and hair health.
March 2024 in “EMBO molecular medicine” Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating TLR9 helps heal large wounds and regrow hair by involving a specific type of immune cell.
July 2022 in “Journal of Investigative Dermatology” Blocking DPP4 can help activate hair growth and improve hair regeneration.
Certain Chinese herbs may help treat kidney fibrosis by targeting TGF-β.
June 2021 in “International journal of cosmetics and dermatology” Vitamin C and E may help with certain skin and hair conditions, but more research is needed to confirm their effectiveness.
March 2021 in “Der Hautarzt” Neuroendocrine paraneoplastic syndromes often show skin changes, helping early diagnosis and requiring a team approach for best care.
April 2017 in “Journal of Investigative Dermatology” HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
238 citations
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March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
September 2016 in “Journal of thoracic and cardiovascular surgery/The Journal of thoracic and cardiovascular surgery/The journal of thoracic and cardiovascular surgery” Creating a supportive environment is crucial for repairing heart tissue without using actual heart cells.
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December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Fibroblast behavior is key for skin structure and healing.
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September 2020 in “Current Rheumatology Reports” Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.
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January 2014 in “BioMed Research International” Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.
January 2026 in “Advanced Healthcare Materials” The new bioreactor improves skin grafts by evenly stretching cells and monitoring conditions for better growth.
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September 2024 in “Science Translational Medicine” New scientific advancements offer hope for better treatments for skin fibrosis.
July 2024 in “Journal of Investigative Dermatology” Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.
A high fat lard diet may protect against skin fibrosis and affect hair growth.