research Signaling pathways in the mechanisms of drug action
Signaling pathways are key targets for developing effective drugs.
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research Type-2 immunity associated with type-1 related skin inflammatory diseases: friend or foe?
Type-2 immunity may influence skin diseases and could be targeted for treatment.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
research Prediction and Demonstration of Retinoic Acid Receptor Agonist Ch55 as an Antifibrotic Agent in the Dermis
Ch55 may help reduce skin scarring and fibrosis.
research Delayed Collagen Production without Myofibroblast Formation Contributes to Reduced Scarring in Adult Skin Microwounds
Microthermal wounds heal with less scarring due to delayed collagen production and minimal inflammation.
research Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling
FR-1 reduces skin scarring and promotes healing without harmful effects.
research Hidradenitis Suppurativa Tunnels: Unveiling a Unique Disease Entity
Hidradenitis suppurativa tunnels worsen the disease and often need surgery because current treatments are not very effective.
research Dermal Hedgehog Signaling in Papillary Fibroblasts: An Emerging Key Player in Skin Regeneration
Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.
research Neutrophil extracellular traps impair regeneration
White blood cells and their traps can slow down the process of new hair growth after a wound.
research Granulocyte colony stimulating factor promotes scarless tissue regeneration
Granulocyte colony stimulating factor helps heal wounds without scars.
research A Review of Metabolic Dysregulation in Lymphocytic Cicatricial Alopecia: Exploring the Connections and Therapeutic Implications
Metabolic issues may trigger lymphocytic cicatricial alopecia, and treatments targeting these issues could help.
research Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair
Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.
research 865 Frontal fibrosing alopecia is associated with dysregulation of cholesterol biosynthesis pathways, fibrosis and mast cells
Frontal Fibrosing Alopecia involves disrupted cholesterol pathways, fibrosis, and increased mast cells.
research Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts
Wnt signaling is disrupted in asthma, affecting cell growth and inflammation.
research 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
3D bioprinting with special hydrogels helps heal wounds and grow new blood vessels.
research Foxn1 in Skin Development, Homeostasis and Wound Healing
Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation
Advancements in wound healing aim to improve personalized treatments and enhance healing outcomes.
research Quantification of mast cells in central centrifugal cicatricial alopecia
Mast cells may significantly contribute to central centrifugal cicatricial alopecia.
research Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
research Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Type 2 immunity helps control mite growth in hair follicles, preventing damage.
research Transcriptome meta-analysis reveals the hair genetic rules in six animal breeds and genes associated with wool fineness
Different sheep breeds share similar genetic factors affecting wool fineness.
research CD44 signaling in skin wound healing and regeneration
CD44 signaling can help heal wounds without scars.
research A probabilistic Boolean model on hair follicle cell fate regulation by TGF-β
TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.
research Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome
Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.
research Skin-inspired phototherapeutic cryogel ameliorates infected wound healing by orchestrating mechanotransduction and immunomodulation
The cryogel effectively heals infected wounds and promotes tissue regeneration without scarring.
research Characteristics and Differences in the Antler Velvet Microbiota During Regeneration
Microbiota changes in deer antler velvet aid in wound healing and tissue regeneration.
research Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing
Softer hydrogels help wounds heal better with less scarring.
research A State-of-the-Art Overview on (Epi)Genomics and Personalized Skin Rejuvenating Strategies
Personalized skin rejuvenation using genomics shows promise but needs more research.