research Targeting a fibrotic bottleneck may provide an opening in the treatment of LUTS
New treatments targeting fibrosis could improve urinary symptoms in BPH.
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960-990 / 1000+ results research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta
Targeting TGFβ can improve skin immunity in older people.
research Trichoscopy
Trichoscopy is a non-invasive way to diagnose hair and scalp problems without needing hair samples.
research Melanocortins in fibroblast biology – current update and future perspective for dermatology
α-MSH may help treat skin inflammation and fibrosis.
research DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms
DHEA reduction may be linked to frontal fibrosing alopecia, but more research is needed.
research Protective effects of taurine on human hair follicle grown in vitro1
Taurine helps protect and promote hair growth.
research Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia
AMT may cause hair loss and changing dWAT activity could help treat it.
research Trichoscopic stages of dissecting cellulitis: a potential complementary tool to clinical assessment
Trichoscopy can help diagnose and monitor the progression of dissecting cellulitis.
research Fibrosing Alopecia in a Pattern Distribution Localized on Alopecia Androgenetica Areas and Unaffected Scalp
A man with hair loss developed a condition causing scarring and inflammation in both bald and non-bald areas of his scalp.
research Erosive Lichen Sclerosus—A Clinicopathologic Subtype
Erosive lichen sclerosus is a distinct subtype with specific skin features, and treatment led to complete resolution in half of the cases.
research Chronic nonhealing ulcer in a finger of a toddler – a rare presentation of the hair thread tourniquet syndrome
A toddler's chronic finger ulcer was successfully treated after removing a hair causing hair-thread tourniquet syndrome.
research The eosinophilia-myalgia syndrome
Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.
research Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing
The Aligned membranes improved wound healing and hair growth with a better immune response in mice.
research Wharton Jelly Hair in a Case of Umbilical Cord Stricture and Fetal Death
Fetal death was caused by umbilical cord stricture with hair growth in the Wharton jelly.
research Solitary Nasal Fibrofolliculoma
A rare, harmless skin tumor was found on a man's nose.
research Clinicopathologic and molecular characterization of a series of sporadic trichoblastic neoplasms
Sporadic trichoblastic neoplasms generally don't recur or spread, with one case showing a specific genetic fusion.
research 0034 Cross-species insights into hair follicle-T cell interactions in discoid lupus erythematosus: A comparison of human, canine and mouse models using spatial transcriptomics
Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.
research EDA Fibronectin Microarchitecture and YAP Translocation During Wound Closure
Correcting EDA fibronectin organization and YAP translocation can improve wound healing in fibrotic conditions.
research Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis
Removing SIX1 in fat cells reduces skin fibrosis.
research ISID1338 - Epidermal growth factor receptor protects from immune privilege collapse and scarring hair follicle destruction
EGFR helps protect hair follicles from damage and scarring.
research 1338 Epidermal growth factor receptor protects from immune privilege collapse and scarring hair follicle destruction
Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
research Male sex hormone and reduced plakoglobin jointly impair atrial conduction and cardiac sodium currents
Male hormones and reduced plakoglobin can impair heart electrical function and increase arrhythmia risk in males.
research Issue Information
Aging causes hair thinning in women due to changes in the scalp environment.
research Epithelial Mesenchymal Transition and Tissue Healing
EMT helps heal tissues but can cause scarring and other issues if prolonged.
research 1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research Nuevas áreas de conocimiento y la problemática documental: la prospectiva de la paz en la Universidad de Granada
ADSC therapy is promising for antiaging skin treatment.
research ACKR2 limits skin fibrosis and hair loss through IFN‐β
ACKR2 helps prevent skin scarring and hair loss by controlling inflammation.
research 1270 Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia
CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.
research Adjuvant use of topical metformin with standard therapies in recalcitrant central centrifugal cicatricial alopecia: A case series
Topical metformin may improve hair regrowth in CCCA when added to standard treatments.
research Rare Gli1+ perivascular fibroblasts promote skin wound repair
Rare Gli1+ fibroblasts are crucial for skin wound healing.