December 2024 in “Advanced Composites and Hybrid Materials” Electrospun 3D nanofibrous materials show promise for bone regeneration in orthopaedics.
December 2023 in “Journal of molecular structure” Hair treatments and dehydration affect hair's lipid and protein behavior, influencing its flexibility and appearance.
35 citations
,
February 2003 in “Biochimica et Biophysica Acta (BBA) - General Subjects” Lead can help reveal and organize lipids in human hair.
8 citations
,
March 2020 in “Colloids and surfaces. B, Biointerfaces” Heating hair proteins changes their structure and may improve their blood clotting ability.
November 2024 in “Biochemical and Biophysical Research Communications” Abnormal gene expression related to keratin causes hair loss in certain mice.
175 citations
,
August 1997 in “Nature Genetics” 79 citations
,
February 2009 in “Human Genetics” 60 citations
,
December 2003 in “Journal of Investigative Dermatology” K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.
50 citations
,
April 2019 in “Journal of Biosciences” 35 citations
,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
14 citations
,
April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
6 citations
,
January 2018 in “Advances in experimental medicine and biology”
2 citations
,
August 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific mutation in the K25 gene causes a rare genetic disorder with curly hair at birth and later hair loss, along with dental issues.
1 citations
,
July 2021 in “IntechOpen eBooks” Environmental factors can cause mutations in skin proteins, leading to skin disorders.
October 2025 in “Frontiers in Veterinary Science” Key proteins affecting cashmere fiber quality were identified for better breeding.
February 2025 in “Animals” Understanding proteins in skin structures like claws and hair is crucial for future research.
13 citations
,
January 2018 in “Advances in experimental medicine and biology” 272 citations
,
September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
235 citations
,
July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
119 citations
,
August 2008 in “BMC Evolutionary Biology” KRTAP genes evolved early in mammals, leading to diverse hair traits.
115 citations
,
November 2008 in “Proceedings of the National Academy of Sciences” Reptiles have genes similar to hair proteins, suggesting hair's genetic origins predate mammals.
114 citations
,
February 2023 in “International Journal of Molecular Sciences” The skin microbiome is crucial for skin health, and more research is needed to explore its role and potential treatments.
106 citations
,
December 2015 in “Biomacromolecules” Keratin hydrogels can be customized for better tissue healing.
100 citations
,
December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
93 citations
,
July 2006 in “Journal of Investigative Dermatology” K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.
75 citations
,
September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
68 citations
,
April 2014 in “Journal of Investigative Dermatology” Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
61 citations
,
September 2024 in “Micromachines” Electrospun nanofiber membranes are promising for non-invasive medical uses like tissue repair and health monitoring.
51 citations
,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
46 citations
,
August 2022 in “Animals” miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.