63 citations
,
July 2006 in “British Journal of Dermatology” Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
53 citations
,
September 2007 in “Annals of the New York Academy of Sciences” Thymosin beta 4 helps hair grow by boosting stem cell activity.
49 citations
,
August 1999 in “Journal of Investigative Dermatology” Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.
47 citations
,
September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
39 citations
,
January 2016 in “PubMed” Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
37 citations
,
February 2005 in “Journal of Investigative Dermatology” Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.
33 citations
,
September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
33 citations
,
July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
31 citations
,
January 2004 in “Methods in cell biology” Hair and follicle keratins differ in structure and expression, especially in cysteine content.
31 citations
,
December 1991 in “Annals of the New York Academy of Sciences” ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.
28 citations
,
November 2018 in “Journal of cellular physiology” miR-124 helps mouse hair follicle stem cells become nerve cells by blocking Ptbp1 and Sox9.
28 citations
,
February 2014 in “Journal of Cutaneous Pathology” Keratoacanthoma changes as it grows, showing different hair follicle characteristics at each stage.
28 citations
,
February 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b helps skin cells and hair grow.
28 citations
,
November 1987 in “Journal of the American Academy of Dermatology” The model successfully grew and differentiated hair follicle cells in the lab.
26 citations
,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
26 citations
,
February 2012 in “Journal of Investigative Dermatology” Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
24 citations
,
November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
23 citations
,
June 2023 in “Cell Reports” Early hair follicle development involves distinct cell populations and Wnt signaling influences cell identity.
22 citations
,
July 2016 in “PLoS ONE” Certain miRNAs and genes influence wave patterns in Hu sheep hair follicles.
22 citations
,
May 2011 in “Molecular Biology of the Cell” Integrin-linked kinase is crucial for normal skin healing.
22 citations
,
September 2001 in “Journal of Investigative Dermatology” S100A8 and S100A9 proteins help form hair shafts during growth.
21 citations
,
September 2010 in “Cancer Prevention Research” Overactive signaling in hair follicles can lead to skin cancer.
20 citations
,
January 2008 in “Journal of Korean Medical Science” NGAL may help maintain skin balance and is linked to skin disorders and cancers.
20 citations
,
January 1995 in “Cells tissues organs” Changing light periods synchronized wool growth cycles in sheep.
18 citations
,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
17 citations
,
September 2018 in “Matrix Biology” Laminin-511 is essential for proper melanocyte movement and development in mice.
16 citations
,
November 2020 in “In Vitro Cellular & Developmental Biology - Animal” Microfollicles can effectively model human hair follicles for research and testing.
16 citations
,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
15 citations
,
July 2015 in “Developmental Dynamics” Orai1 protein is crucial for tooth development and affects enamel thickness and mineralization.