854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
97 citations
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
85 citations
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June 2017 in “Journal of Investigative Dermatology” Blimp1 is crucial for hair follicle growth and skin health.
72 citations
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July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
61 citations
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October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
53 citations
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May 1990 in “Journal of Dermatology” Minoxidil speeds up hair growth in rats without prolonging growth phase.
22 citations
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October 2019 in “International Journal of Nanomedicine” The nanoparticles improved hair growth and enlarged hair bulbs.
22 citations
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February 2002 in “Journal of theoretical biology” The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
14 citations
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January 2012 in “International Journal of Trichology” Hodgkin's lymphoma can show up as hair loss.
11 citations
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January 2018 in “Annals of Dermatology” Some people experienced temporary hair loss after hair transplant surgery but recovered fully within 10 months.
9 citations
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June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
5 citations
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August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
5 citations
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February 2015 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” OCT can non-invasively diagnose follicular keratosis and other hair follicle disorders.
5 citations
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October 1988 in “Clinics in Dermatology” Minoxidil promotes hair growth but exact mechanism is unknown.
3 citations
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February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
3 citations
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January 2018 in “Journal of South Asian Federation of Obstetrics and Gynaecology” Letrozole is better for single follicle development and endometrial thickness in PCOS, with no significant difference in pregnancy rates compared to clomiphene.
3 citations
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May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
April 2026 in “International Journal of Impotence Research” Anabolic steroid abuse can cause sexual, fertility, and health problems.
February 2026 in “International Journal of Molecular Sciences” 3-Hydroxypropionic acid may help treat hair loss by promoting hair growth in cells.
March 2025 in “International Journal of Trichology” Storing hair follicles in 10% DMEM at 37°C improves hair transplant success.
December 2024 in “Era s journal of medical research” Genetic variants in CYP genes may worsen PCOS symptoms.
October 2024 in “Journal of Cosmetic Dermatology” Reducing miR-30a-5p helps hair follicle stem cells grow and survive.
August 2020 in “Nigerian journal of paediatrics” A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.
January 2016 in “Springer eBooks” A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.
June 2012 in “Nature digest” A substance called prostaglandin D2 is linked to stopping hair growth in men with common baldness.
November 2004 in “Medical Journal of Indonesia” Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.
October 2015 in “Elsevier eBooks” Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
6 citations
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April 2019 in “Endocrinology and Metabolism Clinics of North America” Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.
October 2006 in “Aging Health” Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.
99 citations
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August 2009 in “Nature Genetics” Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.