19 citations
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January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
August 2023 in “Scientific reports” Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
25 citations
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October 2005 in “PubMed” Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
Rat hair follicle bulge cells can become nerve and glial cells, showing potential for neuroprotection.
50 citations
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September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
26 citations
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July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
6 citations
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April 2024 in “Journal of Investigative Dermatology” CRISPR-based tools improve understanding and treatment of skin development and conditions.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
75 citations
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September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
13 citations
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July 2020 in “World journal of stem cells” Vitamin D and calcium are important for skin stem cell function and wound healing.
57 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
268 citations
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December 2003 in “Experimental Dermatology” Hair follicle cells can become fat and bone cells.
6 citations
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February 2010 in “Biotechnology and bioprocess engineering” Using umbilical cord stem cells can help create hair-growing tissues more affordably.
Stem cells play a key role in nonmelanoma skin cancers, with different origins and genetic changes linked to basal and squamous cell carcinomas.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
142 citations
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
37 citations
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January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
February 2026 in “Journal of Cellular Physiology” TGF-β3 controls stem cell growth and development, varying by cell type and conditions.
10 citations
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January 2020 in “Acta Neurobiologiae Experimentalis” Valproic acid and crocin together boost cell growth and may help treat nerve injuries.
January 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Adding Y-27632 and bFGF to the culture medium greatly improves goat hair follicle stem cell growth and quality.
11 citations
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February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
191 citations
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September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
5 citations
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March 2023 in “PubMed” Advanced therapy medicinal products show promise for vitiligo treatment with fewer side effects, but affordability is a challenge.
66 citations
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March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
2 citations
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January 2025 in “动物学研究” YAP1 helps fat cell formation by influencing the Hippo pathway.
156 citations
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January 1989 in “Genes & Development” Keratin expression reflects cell organization and differentiation, not causes it.
29 citations
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March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.
16 citations
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February 2013 in “Molecular Medicine Reports” CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
50 citations
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October 2011 in “Archives of Biochemistry and Biophysics” Vitamin D receptor is essential for healthy hair growth.
165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.