848 citations
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October 2020 in “International Journal of Molecular Sciences” PRP shows promise in treating joint and spine issues, but translating lab results to humans is challenging.
321 citations
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January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
222 citations
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August 2009 in “Experimental Dermatology” Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
212 citations
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January 2017 in “Mediators of Inflammation” Stem cells show promise in speeding up wound healing and tissue regeneration.
132 citations
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
129 citations
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
51 citations
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October 2024 in “Pharmaceutics” Improving drug delivery through the skin requires understanding skin and using enhancers.
50 citations
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September 2023 in “Biomarker Research” S100A6 is important for cell functions and can help diagnose and treat diseases.
44 citations
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July 2020 in “Stem Cell Research & Therapy” Epidermal stem cells show promise for skin repair and regeneration.
37 citations
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
37 citations
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August 2020 in “BMC Genomics” Hair greying is mainly influenced by age, with genetics playing a smaller role.
35 citations
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January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
34 citations
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November 2023 in “Applied Materials Today” Nanoemulsions can effectively treat skin cancer with fewer side effects.
34 citations
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January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
33 citations
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October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
32 citations
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April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
31 citations
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August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
30 citations
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February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
29 citations
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January 2021 in “Journal of nanobiotechnology” Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
28 citations
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June 2020 in “ACS Biomaterials Science & Engineering” The new ECM patch greatly improves wound healing and tissue regeneration.
27 citations
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February 2023 in “Frontiers in Cell and Developmental Biology” WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
27 citations
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October 2020 in “Biomedicine & Pharmacotherapy” Hair follicle stem cells help skin heal and grow better.
26 citations
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January 2025 in “iScience” PRP helps tissue repair but lacks standard preparation methods.
22 citations
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March 2023 in “Bioengineering” Stem cell therapies may help improve symptoms and quality of life for people with epidermolysis bullosa.
22 citations
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December 2013 in “Stem cells and development” Horse skin stem cells combined with platelet-rich plasma improve skin healing.
20 citations
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August 2022 in “Frontiers in Immunology” Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
20 citations
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December 2019 in “International Journal of Molecular Sciences” HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.
18 citations
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August 2023 in “Journal of Cell Science” Understanding metabolic changes in dormant cells can help treat cancer.