21 citations
,
December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
12 citations
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January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
Ganoderma lucidum extract may help treat stress-related hair loss.
2 citations
,
August 2024 in “Indian Dermatology Online Journal” Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.
56 citations
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March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
14 citations
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May 2017 in “InTech eBooks” Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
November 2023 in “International Journal of Trichology” A rare form of lupus caused hair loss and skin bumps, diagnosed through biopsy, improved partially with treatment.
56 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
2 citations
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November 2024 in “JAAD reviews.” Certain drugs can change hair color, either lightening or darkening it.
41 citations
,
July 2016 in “Journal of Investigative Dermatology” Dysplastic nevi have unique gene expressions, making them distinct from common melanocytic nevi.
22 citations
,
January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
Atopic dermatitis affects the appearance of skin reactions, making certain features more common and improving diagnostic accuracy with dermoscopy.
December 2025 in “Biomedicines” Tyrosine kinase inhibitors for endocrine tumors often cause skin issues, requiring early management and treatment adjustments.
18 citations
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October 2022 in “Biomedicines” Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
4 citations
,
May 2025 in “International Journal of Nanotechnology and Nanomedicine” Nanocarriers show promise for improving skin drug delivery in treating skin conditions.
April 2025 in “Clinical Dermatology Review” Trichoscopy is effective for diagnosing hair and scalp disorders without invasive biopsies.
134 citations
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July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
26 citations
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January 2018 in “Annals of dermatology/Annals of Dermatology” Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
6 citations
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September 2025 in “Cosmetics” Laser-Assisted Exosome Delivery showed early skin improvement without side effects, but more research is needed.
October 2023 in “Journal of Indian System of Medicine” Ayurveda can help treat premature hair graying with lifestyle changes and herbal remedies.
November 2025 in “Journal of Clinical Medicine” Alopecia areata patients should have eye check-ups due to increased risk of eye problems.
January 2024 in “Skin appendage disorders” Environmental pollutants can damage hair health and cause hair loss.
A new mutation in the TRPS1 gene caused Trichorhinophalangeal syndrome in a 17-year-old, highlighting the need for genetic testing.
1 citations
,
March 2024 in “International journal of molecular sciences” Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
68 citations
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May 2024 in “International Journal of Molecular Sciences” Personalized acne treatments and new therapies show promise for better results.
20 citations
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October 2024 in “British Journal of Dermatology” The guideline provides recommendations for managing alopecia areata effectively.
17 citations
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July 2019 in “Lupus Science & Medicine” Plucked hair follicles can help diagnose scalp lupus.
4 citations
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March 2023 in “Current Oncology” Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.
3 citations
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January 2019 in “International Journal of Trichology” The balance of thiol-disulfide in women with hair loss is affected but not damaged.
November 2025 in “British Journal of Dermatology” The guideline recommends personalized treatment for alopecia areata, including new oral medications and psychological support.