research LB1774 Establishing competent morphogenetic fields for tissue pattern regeneration in skin organoids
Skin organoids can regenerate hair by forming specific cell units with certain signals.
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research Follistatin and secreted frizzled-related protein 1, OVO homolog-like 1-regulated genes, are important for hair follicle neogenesis
Certain genes controlled by OVOL1 are crucial for creating new hair follicles.
research Follicular dermal papilla structures by organization of epithelial and mesenchymal cells in interfacial polyelectrolyte complex fibers
Scientists created 3D hair-like structures that could help study hair growth and test treatments.
research Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration
Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system
Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1
Hair follicle stem cells can become corneal-like cells with the help of pax6.
research Genome-wide expression profile analysis of 3D cultured dermal papilla cells from patients with androgenic alopecia
Hair loss in androgenic alopecia patients is linked to changes in certain genes that control cell growth and death.
research Notes from the Editor Emeritus
Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
research Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles
Stem cells in developing hair follicles move to specific areas as they mature.
research Neural Potential of a Stem Cell Population in the Hair Follicle
Stem cells in hair follicles can become various cell types, including neurons.
research 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium
Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
research Keratins of the human hair follicle: “Hyperproliferative” keratins consistently expressed in outer root sheath cells in vivo and in vitro
Outer root sheath cells consistently express certain keratins influenced by their environment.
research Soluble factors from human hair papilla cells and dermal fibroblasts dramatically increase the clonal growth of outer root sheath cells
research Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach
The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.
research The ultrastructure of the interfollicular epidermis of the hairless (hr/hr) mouse
research Localization of Skin Stem Cells of Inner Mongolia Cashmere Goats
Stem cells in cashmere goats are found in hair follicles and have a slow growth rate.
research Two- and Three-Dimensional Culture of Keratinocyte Stem and Precursor Cells Derived from Primary Murine Epidermal Cultures
research Cultured human and rat tooth papilla cells induce hair follicle regeneration and fiber growth
Tooth papilla cells can help regenerate hair follicles and grow hair.
research Gene expression profiling gets to the root of human hair follicle stem cells
Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
research [Hair follicle regeneration after implantation of hair follicle cells into subcutis of nude mice].
Hair follicle-like structures can form when specific hair cells are mixed and implanted in mice.
research Perifollicular vascularization: Cocultures and tricultures approaches to study the cross-talk between microvascular endothelial cells, follicle papilla cells and keratinocytes
Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
research Harnessing the intradermal delivery of hair follicle dermal papilla cell spheroids for hair follicle regeneration in nude mice
Delivering specific cell clusters into the skin can help regrow hair in mice.
research Study of Constructing Tissue Engineered Urethra Membrane Using Hair Follicle Stem Cells and Nano Silk Fiber in Vitro
Rabbit hair follicle stem cells and nano silk fibers can create a tissue-engineered urethra.
research “Dark Cells” in Normal, Hyperplastic, and Promoter-Treated Mouse Epidermis Studied by Conventional and High-Voltage Electron Microscopy
research FGF22 Secreted by Hair Papilla Cells Regulates Hair Follicle Stem Cell Proliferation and Differentiation
FGF22 helps hair follicle stem cells grow and develop.
research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
research 504 Angiogenic capabilities driven by dermal papilla cells and their modulation by androgen action
Androgens reduce hair growth by affecting cell differentiation and blood vessel formation.
research In vitro induction of hair follicle signatures using human dermal papilla cells encapsulated in fibrin microgels
Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.