research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
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research Original article / Article original External post mortem artefact: a key issue in hair result interpretation
Hair test results can be misleading due to external contamination, so they shouldn't be used alone to assess long-term drug use.
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
research The pathophysiology of polycystic ovary syndrome
Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
research Volatile signalling by sesquiterpenes from ectomycorrhizal fungi reprogrammes root architecture
Fungi-produced compounds can change plant root growth.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology
Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
research Review of the effects of 17α-estradiol in humans: a less feminizing estrogen with neuroprotective potential
17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
research Final Report on the Safety Assessment of Hypericum Perforatum Extract and Hypericum Perforatum Oil
St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.
research Congenital adrenal hyperplasia
CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days
Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
research Evaluation of the 5α-reductase inhibitor finasteride on reproduction and gonadal development in medaka, Oryzias latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Eclipta prostrata (L.) L. (uses and bioactivities)
Eclipta prostrata is used for health benefits and hair care, showing various protective and healing effects.
research Serum C-19 steroid sulphates in females with clinical hyperandrogenism
Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
research An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects
Herbal formula shows promise for hair loss treatment.
research Sphingolipids of the Murine Hair
Murine hair has specific types of ceramides and glucosylceramides but lacks acylceramides.
research Synthesis of Cu 4 O 3 nanoparticles using pumpkin seed extract: Optimization, antimicrobial, and cytotoxicity studies
Pumpkin seed extract can create copper oxide nanoparticles with potential antibacterial and cancer-fighting properties.
research Traditional uses, phytochemistry, pharmacology, toxicity and clinical application of traditional Chinese medicine Cynoglossum amabile: a review
Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
research Quantitative determination of nutraceuticals in matured unriped fruits of three edible Musa Species using GC-MS
Unripe fruits of three banana species have many health-boosting compounds useful for medicine.
research Characteristics of Cut Head Hair: An Evidence in Criminal Investigations
Cut hair can help link suspects to crime scenes.
research Developing formulations designed to deliver antiseptic agents to target sites within the skin
Nanoemulsions can effectively deliver antiseptic agents deep into the skin.
research ANTINOCICEPTIVE ACTIVITY OF ADIANTUM CAPILLUS IN EXPERIMENTAL ANIMALS
Adiantum capillus extract reduces pain and swelling in animals.
research Optimization of ultrasound-assisted extraction of bioactive compounds from Carthamus caeruleus L. rhizome: Integrating central composite design, Gaussian process regression, and multi-objective Grey Wolf optimization approaches
Optimal conditions for extracting beneficial compounds from Carthamus caeruleus L. rhizomes were identified, improving efficiency.
research A comprehensive review of biochemical factors in herbs and their constituent compounds in experimental studies on alopecia
Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
research Extracts and Fractions with antifungal potential for the treatment of hair disorders
Medicinal plants can treat hair disorders by fighting fungi and improving hair health.
research PHYTOCHEMICAL ANALYSIS AND ASSESSMENT OF THE ANTIOXIDANT, HEMOLYTIC, AND ANTIBACTERIAL PROPERTIES OF LEAVES AND RHIZOMES OF CARTHAMUS CAERULEUS L.
The study on Carthamus caeruleus L. reveals that its leaves and rhizomes contain significant bioactive compounds, with leaves showing higher levels of phenolic and flavonoid compounds, while rhizomes are richer in tannins. Leaf extracts demonstrated superior antioxidant and antibacterial activity, with antioxidant potential comparable to BHT and a minimum inhibitory concentration (MIC) ranging from 0.6 to 5 mg/mL against various bacteria. Hemolytic activity ranged from 0.86% to 14.45%. These findings suggest that C. caeruleus leaves could be a valuable source of natural antioxidants and antibacterial agents, with potential applications in developing therapeutic agents for oxidative stress, bacterial infections, wound healing, and as natural supplements. Further research is needed to understand the specific roles of individual phytochemicals in these bioactivities.
research Testosterone Therapy in Women: A Literature Review of Clinical Indications, Dosing, Routes of Administration, and Safety
Testosterone therapy can safely and effectively treat symptoms like low libido and fatigue in women, especially after menopause.
research Prostaglandin D 2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee
Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.