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Did you mean Histone Methylation?

GlossaryHistone Methylation

process adding methyl groups to histone proteins, affecting gene expression

Histone methylation is a biological process where methyl groups are added to histone proteins, which help package DNA in cells. This modification can either activate or repress gene expression, influencing how genes are turned on or off. For professionals, it's a key epigenetic mechanism that affects chromatin structure and function, playing a crucial role in development, differentiation, and disease.

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research Molecular characterization of HOXC8 gene and methylation status analysis of its exon 1 associated with the length of cashmere fiber in Liaoning cashmere goat

20 citations , January 2017 in “Genetica”

The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.

Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia

research Evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia

24 citations , March 2011 in “British Journal of Dermatology”

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

research Association between DNA Methylation in the Core Promoter Region of the CUT-like Homeobox 1 (CUX1) Gene and Lambskin Pattern in Hu Sheep

1 citations , September 2023 in “Genes”

DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.

research Genome-wide DNA methylation and transcriptome analyses reveal the key gene for wool type variation in sheep

1 citations , July 2023 in “Journal of Animal Science and Biotechnology”

The SOSTDC1 gene is crucial for determining sheep wool type.

research Decreased Androgen Receptor Gene Methylation in Premature Pubarche: A Novel Pathogenetic Mechanism?

53 citations , January 2006 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Reduced AR gene methylation may cause early pubic hair growth in girls.

Possible Role of Osteopathic Manipulation Treatment in Alleviating Finasteride-Induced Dementia Through Modulation of HOMER-3 Gene Methylation

research Possible Role of Osteopathic Manipulation Treatment in Alleviation of Finasteride-Induced Dementia through Modulation of HOMER-3 Gene Methylation

May 2025 in “Physiology”

Osteopathic manipulation therapy might help treat dementia caused by finasteride.

research N6-methyladenosine (m6A)-circHECA from secondary hair follicle of cashmere goats: identification, regulatory network and expression regulated potentially by methylation of its host gene promoter

2 citations , August 2024 in “Animal Bioscience”

m6A-circHECA may affect cashmere goat hair growth and is possibly controlled by gene promoter methylation.

Reshaped DNA Methylation Cooperating with Homoeolog-Divergent Expression Promotes Improved Root Traits in Synthesized Tetraploid Wheat

research Reshaped DNA methylation cooperating with homoeolog‐divergent expression promotes improved root traits in synthesized tetraploid wheat

February 2024 in “New phytologist”

DNA changes in tetraploid wheat improve root growth and nitrogen use.

research Global expression profile and global genome methylation signatures in male patients with androgenetic alopecia

2 citations , December 2019 in “Journal of The European Academy of Dermatology and Venereology”

Differences in gene expression and methylation patterns found in AGA patients suggest potential targets for future treatments.

research Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome

1 citations , January 2021 in “Vide Leaf, Hyderabad eBooks”

Altered DNA methylation may be a marker for Polycystic Ovary Syndrome.

research Finasteride Induces Epigenetic Alteration of TMPRss2 Gene Expression: A Potential role in Severe Acute Respiratory Syndrome-Corona Virus-2 Inhibition

May 2023

Finasteride may help reduce COVID-19 infection by altering a key gene.

DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Chromatin Topology in Lineage-Specific Loci to Control Keratinocyte Differentiation and Hair Growth

research 1440 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control keratinocyte differentiation and hair growth

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Tet2 and Tet3 enzymes are important for controlling hair growth and shape by affecting gene activity and DNA structure in hair follicles.

DNA Dioxygenases Tet2/3 Regulate Gene Promoter Accessibility and Three-Dimensional Chromatin Topology in Lineage-Specific Loci to Control Hair Growth

research 723 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and three-dimensional chromatin topology in lineage-specific loci to control hair growth

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Tet2 and Tet3 enzymes are essential for controlling hair growth by affecting DNA demethylation and gene expression in mice.

research Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats

39 citations , January 2020 in “Frontiers in Genetics”

PDGFC gene may help select goats with desirable curly wool traits.

LncRNA-599547 Contributes to the Inductive Property of Dermal Papilla Cells in Cashmere Goats Through miR-15b-5p/Wnt10b Axis

research LncRNA-599547 contributes the inductive property of dermal papilla cells in cashmere goat through miR-15b-5p/Wnt10b axis

7 citations , August 2020 in “Animal biotechnology”

A specific RNA in cashmere goats helps improve hair growth by interacting with certain molecules.

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

research Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat

24 citations , April 2020 in “Cells”

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Identifying Molecular Targets for Reverse Aging Using Integrated Network Analysis of Transcriptomic and Epigenomic Changes During Aging

research Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging

12 citations , June 2021 in “Scientific Reports”

Curcumin may help reverse aging by targeting specific genes.

research Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep

112 citations , September 2021 in “BMC Biology”

Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.

research Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory

22 citations , January 2017 in “Advanced Healthcare Materials”

The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.

research Tailored chromatin modulation to promote tissue regeneration

10 citations , May 2019 in “Seminars in Cell & Developmental Biology”

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

research Novel Insights to Assess Climate Resilience in Goats Using a Holistic Approach of Skin-Based Advanced NGS Technologies

June 2023 in “International journal of molecular sciences”

Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.

LncRNA-000133 from Secondary Hair Follicle of Cashmere Goat: Identification, Regulatory Network, and Its Effects on Inductive Property of Dermal Papilla Cells

research LncRNA-000133 from secondary hair follicle of Cashmere goat: identification, regulatory network and its effects on inductive property of dermal papilla cells

18 citations , January 2019 in “Animal Biotechnology”

A newly found RNA in Cashmere goats may play a role in hair growth and development.

research Epigenetic modifications may explain the relative protection of occipital hair follicles from androgenetic alopecia in men

1 citations , July 2011 in “Hair transplant forum international”

Epigenetic changes might protect occipital hair from male pattern baldness.

research Promoter Methylation Changes in KRT17: A Novel Epigenetic Marker for Wool Production in Angora Rabbit

2 citations , May 2022 in “International journal of molecular sciences”

Changes in KRT17 gene activity linked to wool production in Angora rabbits.

research Androgens and androgen receptor action in skin and hair follicles

100 citations , September 2017 in “Molecular and Cellular Endocrinology”

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

research Epigenetic regulation in adult stem cells and cancers

20 citations , January 2013 in “Cell & Bioscience”

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

research The Role of BMP7 in the Proliferation of Hu Sheep Dermal Papilla Cells Is Influenced by DNA Methylation

June 2024 in “Animals”

DNA methylation affects BMP7 gene expression, influencing cell growth in Hu sheep.

research DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat

January 2023 in “Advanced Biology”

DNA methylation changes affect gene expression during esophageal healing with silk grafts in rats.

Methylation of CpG Islands in Promoter of Type 2 5-Alpha Reductase and Implications of Finasteride Resistance for BPH Therapy

research 102 Methylation of CpG islands in promoter of type 2 5-α reductase and implications of finasteride resistance for BPH therapy

March 2016 in “European Urology Supplements”

Methylation in specific gene region causes finasteride resistance in some BPH patients.

research Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

153 citations , June 2015 in “GenomeBiology.com”

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.