research Lipedematous Scalp Occurring in Two Female Siblings: Further Evidence for a Genetic Role
Lipedematous scalp may have a genetic link and could be associated with psychiatric conditions.
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research Diverse northern Asian and Jomon-related genetic structure discovered among socially complex Three Kingdoms period Gaya region Koreans
The DNA of ancient Koreans from the Three Kingdoms period shows a mix of northern Chinese and Japanese-Jomon ancestry, revealing two distinct genetic groups.
research Systematic investigation of a potential epidemiological and genetic association between male androgenetic alopecia and COVID‐19
No significant link between male pattern baldness and COVID-19 severity was found.
research Craniometric Ancestry Proportions among Groups Considered Hispanic: Genetic Biological Variation, Sex-Biased Asymmetry, and Forensic Applications
Topical minoxidil effectively promotes hair regrowth in male pattern baldness.
research Whole-genome resequencing to investigate the genetic diversity and the molecular basis underlying key economic traits in indigenous sheep breeds adapted to hypoxic environments
Tibetan sheep have specific genes for high-altitude adaptation and wool traits, aiding breeding strategies.
research A Review on Unraveling the Complexity of Autoimmune Skin Disorders: Genetic Influences, Environmental Triggers and Innovative Management Approaches
Autoimmune skin disorders are caused by genetic and environmental factors and are treated with various medications and preventative strategies.
research A Study on the Pattern of Genetic Inheritance of Polycystic Ovarian Syndrome
PCOS and related metabolic issues often run in families.
research Deciphering the cellular landscape and genetic underpinnings of fiber diameter determined by dermal papilla cells in fine-wool sheep
This study used single-cell RNA sequencing on skin tissues from six fine-wool sheep to explore the molecular mechanisms regulating hair follicle development and fiber diameter. A transcriptional atlas of the hair follicle microenvironment was constructed, identifying 14 distinct cell types and revealing that the ultra-fine wool group had a higher proportion of dermal papilla cells (DPCs), hair follicle stem cells, and outer root sheath cells. The study highlighted the role of DPCs in hair follicle growth, identifying three distinct states of DPCs and analyzing differentially expressed genes, such as CRABP1, which influences DPC proliferation. These findings provide insights into hair follicle biology and potential molecular targets for breeding ultra-fine wool sheep.
research Large-Scale Plasma Proteomics and Genetic Integration Uncover Novel Biological Pathways in Male Pattern Baldness
New biological pathways and potential treatment targets for male pattern baldness were identified.
research BH26 First reported case of lichen planopilaris in siblings: evidence for a genetic link?
Lichen planopilaris may have a genetic link.
research Tru9I Variant as a Novel Genetic Marker for Vitamin D Deficiency in Alopecia Areata
The Tru9I variant in the VDR gene may influence alopecia areata risk and vitamin D levels.
research Identificación de la variación molecular y genética subyacente a las enfermedades de la piel
Non-coding RNAs may be key in diagnosing and treating rare skin disorders.
research Biomedical applications of organoids in genetic diseases
Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
research Landmark native breed of the Orenburg goats: progress in its breeding and genetics and future prospects
The Orenburg goat breed has unique genetics that require more detailed research and careful breeding.
research Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease
The research provided new insights into the genetic factors contributing to hair loss and skin conditions by analyzing individual cells from the human scalp.
research Meeting Report: 68th Montagna Symposium on the Biology of Skin “Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology”
The symposium highlighted the importance of genetics in understanding and treating complex skin diseases.
research Assessment of The Influence of Non-Genetic Risk Factors on The Disease Onset and Progression of Androgenetic Alopecia in Egyptian Males
Avoiding smoking, stress, obesity, and poor diet may help reduce hair loss in young Egyptian males.
research Androgenetic alopecia risk IDed with genetic test
research Variability of Retail Pricing of Generic Urologic Medications in a Major US Metropolitan Area
Independent pharmacies generally offer lower prices for certain generic urologic medications than chain pharmacies.
research Purpose-limited pharmaceutical product claims under the revised European Patent Convention: A camouflaged attack on generic substitution?
The revised European Patent Convention may limit generic drug use, affecting healthcare professionals' treatment choices.
research MP27-18 STATEWIDE GEOGRAPHIC PRICE VARIATION OF GENERIC BPH MEDICATIONS
Big chain pharmacies in Pennsylvania charge significantly more for generic BPH medications than independent pharmacies, but independent pharmacies have more regional price variation.
research The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches
Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.
research Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen
The research identified new skin traits in mice, some linked to human skin conditions.
research In Search of New Therapeutics—Molecular Aspects of the PCOS Pathophysiology: Genetics, Hormones, Metabolism and Beyond
New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
research Finasteride inhibits the progesterone-induced spike-wave discharges in a genetic model of absence epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Congenital Zinc Deficiency from Mutations of theSLC39A4Gene as the Genetic Background of Acrodermatitis Enteropathica
A Korean boy's skin and digestive symptoms were caused by a rare genetic disorder that affects zinc absorption, and he got better with zinc supplements.
research Deep facial mycosis due to Trichophyton verrucosum—molecular genetic identification of the dermatophyte in paraffin‐embedded tissue—case report and review of the literature
An 80-year-old man's deep beard infection was cured with oral terbinafine after identifying the fungus Trichophyton verrucosum.
research Clinical Management of Prostate Cancer in High-Risk Genetic Mutation Carriers
More research and guidelines are needed for managing prostate cancer in people with high-risk genetic mutations.
research The idiosyncratic genome of Korean long-tailed chicken as a valuable genetic resource
Korean long-tailed chickens have unique genes valuable for ornamental breeding.
research Bloch-Sulzberger Syndrome: A Rare X-Linked Dominant Genetic Disorder in a Newborn
Bloch-Sulzberger Syndrome, or Incontinentia Pigmenti (IP), is a rare X-linked dominant genetic disorder primarily affecting the skin, but it can also impact the central nervous system, eyes, hair, nails, and teeth. The document discusses a case of a 12-day-old female with cutaneous symptoms of IP, emphasizing the importance of early diagnosis based on skin manifestations. Early detection is critical for timely intervention to prevent severe complications in other organs.