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Creating evidence-based guidelines for gender incongruence is difficult due to the personalized nature of transgender medicine.

Removing both ovaries treated the woman's excess male hormone symptoms.

GnRH agonist effectively diagnoses and treats postmenopausal hyperandrogenism from ovarian sources.

The patient with severe hirsutism improved after being diagnosed with non-classic congenital adrenal hyperplasia and treated with corticosteroids.

Hyperandrogenism does not affect young women's sexual function.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Keloids on the penis are rare, often triggered by circumcision, and rarely recur after surgery.

Facial feminization surgery is safe and patients are satisfied, but more detailed research is needed.

Leydig cell tumors can cause high testosterone and symptoms in postmenopausal women, and removing them improves symptoms.

Hirsutism in females is complex, often linked to tumors, and requires more research for better treatment.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

Over-the-counter products can help with menopause symptoms, but be aware of their ingredients.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

The study found that imaging might miss small ovarian tumors causing high testosterone, and suggested using certain testosterone levels and treatment responses to identify these tumors.

Potential androgen excess signs vary by demographics and health, needing inclusive evaluation.

Hirsutism, excessive hair growth in women, is often caused by polycystic ovarian syndrome and is treated by targeting the cause, lifestyle changes, and medication.

Hormone therapies improve mental health and quality of life for those with gender dysphoria.

Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.

A six-year-old girl has early signs of puberty, needs no treatment, but requires regular check-ups for future health risks.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Gynecomastia and premature thelarche often resolve naturally but need evaluation to rule out serious issues.

More research is needed to improve lower body gender affirmation techniques.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

Hormone therapy in transgender and gender diverse individuals affects hair loss differently than in cisgender individuals.

Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.

In PCOS, high male hormones cause hair growth, acne, and hair loss, affecting periods.