research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
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research The effect of plasma rich in growth factors combined with follicular unit extraction surgery for the treatment of hair loss: A pilot study
Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.
research Diagnostic applications and therapeutic option of Cascade CRISPR/Cas in the modulation of miRNA in diverse cancers: promises and obstacles
CRISPR/Cas systems show promise for cancer treatment by targeting miRNAs, but delivery and specificity challenges remain.
research Immunological aspects and gender bias during respiratory viral infections including novel Coronavirus disease‐19 (COVID‐19): A scoping review
Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.
research Overexpression of alfalfa SIMK promotes root hair growth, nodule clustering and shoot biomass production
Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.
research Anti-Zika Activity of a Library of Synthetic Carbohydrate Receptors
Some synthetic carbohydrate receptors, especially compounds 3 and 15, show strong potential for treating Zika virus.
research Experimental and early investigational drugs for androgenetic alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Deletion analysis of AGD1 reveals domains crucial for its plasma membrane recruitment and function in root hair polarity
AGD1's PH domain is essential for its role in root hair growth and polarity.
research Association of mtDNA M/N haplogroups with systemic lupus erythematosus: a case-control study of Han Chinese women
The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.
research The possible implication of the S250C variant of the autoimmune regulator protein in a patient with autoimmunity and immunodeficiency: in silico analysis suggests a molecular pathogenic mechanism for the variant
The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
research Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion
Testosterone helps human pancreatic cells increase insulin release.
research An Investigation into the Effects of Water- and Fat-Soluble Vitamins in Alzheimer's and Parkinson's Diseases
Vitamin E and C may help slow Alzheimer's and Parkinson's progression.
research Coenzyme Q10 phospholipidic vesicular formulations for treatment of androgenic alopecia:ex vivopermeation and clinical appraisal
Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.
research Frontal fibrosing alopecia and genital Lichen sclerosus: Single‐center experience
Frontal fibrosing alopecia may be linked to genital Lichen sclerosus through an autoimmune process.
research Alterations in transcriptome and antioxidant activity of naturally aged mice exposed to selenium-rich rice
Eating selenium-rich rice improved antioxidant activity and signs of aging in mice.
research Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin
Lack of cystatin M/E causes thin hair and dry skin.
research Embryonic-like regenerative phenomenon: wound-induced hair follicle neogenesis
New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
research Pathophysiology of the Burn Scar
Burn scars heal abnormally and more research is needed to find better treatments.
research An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
Zinc helps manage skin disorders and deficiencies can worsen some conditions.
research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hrrh-R) in the Hairless Gene (Hr)
A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
research CircRNA-0100 positively regulates the differentiation of cashmere goat SHF-SCs into hair follicle lineage via sequestering miR-153-3p to heighten the KLF5 expression
A circular RNA helps cashmere goat hair cells become hair follicles by blocking a molecule to boost a gene important for hair growth.
research Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair
Collagen XVII is important for skin aging and wound healing.
research COVID-19 pandemic: what about the gonads?
COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
research Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Therapeutic potential of endogenous stem cells and cellular factors for scar-free skin regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies
Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.
research Evolving approaches to profiling the microbiome in skin disease
New technologies help us better understand how skin microbes affect skin diseases.
research Gap junctions in Turing-type periodic feather pattern formation
Gap junctions help control feather pattern formation in chickens.
research The role of vasoactive peptides in skin homeostasis—focus on adiponectin and the kallikrein-kinin system
Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.