July 2017 in “D-Scholarship@Pitt (University of Pittsburgh)” Notch signaling stops Merkel cell development, and hair follicles help maintain them after skin injury.
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June 1983 in “Journal of Investigative Dermatology” The enzyme is crucial for skin cell development and can be activated without proteolytic activation.
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May 2008 in “Journal of Visualized Experiments” Mouse Epidermal Neural Crest Stem Cells can become various cell types.
August 1993 in “Journal of Dermatological Science” 48 citations
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March 2010 in “PloS one” C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
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December 1991 in “Annals of the New York Academy of Sciences” ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
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January 2004 Stem cells help heal skin wounds by supporting tissue repair and regeneration.
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April 2008 in “Archives of Dermatological Research” Encapsulated human hair cells can substitute for natural hair cells to grow hair.
Epidermal growth factor speeds up hair cell regeneration in chickens after gentamicin damage.
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.
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May 2003 in “Journal of Investigative Dermatology” Human skin can produce steroids from cholesterol.
February 2026 in “Frontiers in Medical Technology” Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
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October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.
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November 2018 in “Archives of Dermatological Research”
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April 2014 in “Experimental Dermatology” Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
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August 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
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January 1984 in “Molecular and Cellular Biochemistry” April 2018 in “Journal of Investigative Dermatology” Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.
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February 1968 in “Australian Journal of Zoology” The southern elephant seal's skin layer helps waterproof the skin by being tightly connected to hair shafts.
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June 2014 in “Journal of developmental biology” Retinoic acid helps change skin cells and is important for skin development and hair growth.
April 2026 in “Frontiers in Cell and Developmental Biology” CD200- cells in hair follicles have a higher ability to regenerate hair.
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April 2004 in “PubMed” Sex steroid receptors are found in specific skin cells, affecting skin and hair functions.
A skin model using hair and skin cells can mimic human skin for research.
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April 2012 in “Journal of Cellular and Molecular Medicine” Telocytes might help with skin repair and regeneration.
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September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
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November 1989 in “The Journal of Cell Biology” Keratin K14 expression varies between hair follicles and epidermis, affecting cell differentiation.
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August 2004 in “Proceedings of the National Academy of Sciences” Hair follicle cells can create new blood vessels in the skin.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
January 2008 in “Di-san junyi daxue xuebao” Rat hair follicle stem cells can become corneal epithelium-like cells when exposed to rabbit corneal limbal stroma.