research High proliferation and delamination during skin epidermal stratification
High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
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research 708 Polycomb-mediated repression and Sonic hedgehog signaling regulate Merkel cell specification
Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.
research Keratinocyte integrin α3β1 induces expression of the macrophage stimulating factor, CSF-1, through a YAP/TEAD-dependent mechanism.
research From Follicle Cell Differentiation and Structure to Chorion Biogenesis in Insects: Cellular Mechanisms, Gene Regulation, Biochemical Composition and Structural Diversity
Insect eggshells form through specialized cell processes and gene regulation, with potential for pest control innovations.
research Reporting Live from the Epidermal Stem Cell Compartment!
The study showed that some hair follicle stem cells wake up to grow hair while others stay asleep, and that the environment around them is important for hair growth.
research Synchronizing actin and microtubules for axonal branching
Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
research Transduction‐induced overexpression of Merkel cell T antigens in human hair follicles induces formation of pathological cell clusters with Merkel cell carcinoma‐like phenotype
Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.
research Fish Acellular Dermal Matrix Promotes Repair of Full‐Thickness Skin Defects in Mice and Bama Pigs
Tilapia skin matrix effectively aids skin wound healing and is a promising option for clinical use.
research “Cellularity as a predictive tool for mesenchymal stem cell concentration in bone marrow concentrates: Implications for regenerative medicine”
Cellularity can estimate mesenchymal stem cell concentration in bone marrow, aiding regenerative medicine.
research A preliminary study of markers for human hair follicle melanin stem cell
Researchers identified potential markers for human hair color stem cells.
research Cardiac Outflow tract septation defects in a DiGeorge syndrome model respond to Minoxidil treatment.
Minoxidil treatment improves heart defects in a DiGeorge syndrome model.
research Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis
Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
research Localization of Skin Stem Cells of Inner Mongolia Cashmere Goats
Stem cells in cashmere goats are found in hair follicles and have a slow growth rate.
research Faculty Opinions recommendation of Application of mesenchymal stem cells derived from bone marrow and umbilical cord in human hair multiplication.
Mesenchymal stem cells from bone marrow and umbilical cord can help regenerate hair follicles.
research A family business: stem cell progeny join the niche to regulate homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
research Decision letter: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation
Fgf20 is crucial for hair follicle formation by influencing cell movement and growth.
research Novel regenerative medicine approaches with the use of adult mesenchymal stem cells: in vitro and in vivo experimental procedures
Adult mesenchymal stem cells show promise in improving tendon, muscle, and skin healing.
research Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin
Integrin α6 helps identify different neural crest cell types in the skin.
research Generation of bioengineered feather buds on a reconstructed chick skin from dissociated epithelial and mesenchymal cells
Scientists created feather buds in lab-grown chick skin using specific cell interactions.
research A notch above bowl: Specification of niche cells in the Drosophila testis
Notch signaling is crucial for specifying niche cells in Drosophila testis.
research 1412 “Telescope model” for coordinated organ morphogenesis and stem cell formation
Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
research Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts
Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
research Bioprinting of Hair Follicle Germs for Hair Regenerative Medicine
Bioprinting hair follicle germs can effectively regenerate hair and improve hair growth.
research Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
research MSCs, but not mesenchymal stem cells
MSCs should be called "master signaling cells" because they mainly help with cell communication and tissue repair.
research Hair follicle-derived mesenchymal cells support undifferentiated growth of embryonic stem cells
Hair follicle cells can help keep embryonic stem cells undifferentiated.
research Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel
cGEL hydrogel improves melanin production in skin cells, making it a promising option for skin treatments.
research Shaping Up Mitochondrion in Motion
Mitochondria change shape to meet energy needs during cell movement.
research An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin
The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
research ZO-1 boosts the in vitro self-renewal of pre-haematopoietic stem cells from OCT4-reprogrammed human hair follicle mesenchymal stem cells through cytoskeleton remodeling
ZO-1 helps hair follicle stem cells renew better by changing their structure.