research Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line
Compounds 6f and 6g effectively stop prostate cancer cell growth without harming healthy cells.
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research Potensi Sinergis Emulgent Topikal Purifikasi Ekstrak Daun Sidr (Ziziphus spina-christi L.) dan Kemiri Bakar (Aleurites moluccanus L.) sebagai Terapi Alopecia
The topical formula with sidr leaves and roasted candlenut extracts significantly boosts hair growth for alopecia.
research Efficacy and safety of a dietary supplement containing a lipid co-extract from Serenoa repens and Pygeum africanum for the treatment of androgenetic alopecia (AGA) in women. Results of a randomized, double-blind, placebo-controlled clinical trial
The supplement with Serenoa repens and Pygeum africanum significantly increased active hair growth and decreased rest phase hair in post-menopausal women with hair loss, with only mild digestive side effects.
research Non-denatured Soybean Extracts in Skin Care: Multiple Anti-Aging Effects
Non-denatured soybean extracts provide multiple anti-aging skin benefits.
research Synergistic Effects of Cinnamomum zeylanicum and Inositol on Metabolic and Hormonal Parameters in Women with Polycystic Ovary Syndrome
Combining cinnamon and inositol improves hormone and metabolism issues in women with PCOS.
research Efficacy, Tolerability, and Superiority of Propylene Glycol-Free, North American Witch-Hazel (Hamamelis virginiana)-Based Solution of 5% Minoxidil Sulfate for the Treatment of Female Androgenetic Alopecia
A witch-hazel-based 5% minoxidil solution is effective and safe for women with hair loss who didn't respond to regular minoxidil, especially if they're sensitive to propylene glycol.
research Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity
Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
research ผลของสารสกัดเปลือกมังคุดต่อเชื้อ Propionibacterium acnes
Mangosteen peel extract effectively inhibits acne-causing bacteria.
research Preparation of ROS ‐Responsive Drug‐Loaded Particles and Microneedles for Diabetic Wounds Healing
Microneedles with green tea polyphenols improve diabetic wound healing.
research Effect of Tocopheryl Polyethylene Glycol Succinate on the Percutaneous Penetration of Minoxidil from Water/Ethanol/Polyethylene Glycol 400 Solutions
Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases
White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
research A review of the sources and pharmacological research of morroniside
Morroniside has many health benefits, including protection against diabetes complications, bone and brain diseases, heart and skin issues, and it supports hair growth and reduces inflammation.
research Tailoring Risperidone-Loaded Glycethosomal In Situ Gels Using Box–Behnken Design for Treatment of Schizophrenia-Induced Rats via Intranasal Route
The new nasal gel for schizophrenia improved drug absorption and brain effects in rats.
research Polymorphism of Keratin Gene KRT71 and Its Relationship with Wool Properties in Gansu Alpine Fine-Wool Sheep
The GG genotype of the KRT71 gene leads to longer wool in Gansu alpine fine-wool sheep.
research Acute oral toxicity and phytochemistry of Catharanthus roseus and Schwenckia americana used as antidiabetic plants in Southern Benin
Catharanthus roseus and Schwenckia americana extracts are generally safe but may cause kidney and liver tissue damage.
research Comparison of Effects on Gene Expression Activity of Low-Molecular-Weight Lychee Fruit Polyphenol (Oligonol®), Adenosine, and Minoxidil in Human Dermal Papilla Cells
Lychee fruit polyphenol (Oligonol®) may regulate genes linked to cell growth and inflammation in human scalp cells.
research Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport
Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
research Fructus Psoraleae Treating in Androgenetic Alopecia Through 5-Α Reductase Inhibition and Nrf2-Keap1 Pathway
Fructus Psoraleae may help treat hair loss by inhibiting 5-α reductase and affecting the Nrf2-Keap1 pathway.
research Aqueous extract of Asiasari radix inhibits formalin-induced hyperalgesia via NMDA receptors
Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
research Skin health promoting effects of a proprietary nutraceutical ingredient (SesZen-BioTM): a placebo controlled, double-blind, and randomized clinical study
SesZen-BioTM improves skin health and reduces signs of aging.
research DIAGNOSTIC AND THERAPEUTIC UTILITY OF GONADOTROPHIN-RELEASING HORMONE AGONIST IN POSTMENOPAUSAL HYPERANDROGENISM OF OVARIAN ORIGIN
GnRH agonist effectively diagnoses and treats postmenopausal hyperandrogenism from ovarian sources.
research The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway
Quercitrin may help treat Alzheimer's by boosting brain cell signaling without causing tumors.
research Screening of Microbial Strains Used to Ferment Dendrobium officinale to Produce Polysaccharides, and Investigation of These Polysaccharides’ Skin Care Effects
Fermenting Dendrobium officinale with Lactobacillus reuteri CCFM8631 increases its skin care benefits.
research A comprehensive overview of Hibiscus-rosa-sinensis and its uses: A review
Hibiscus rosa sinensis is beneficial for health due to its therapeutic properties and is generally safe.
research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
research Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase
Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
research Exploring the Antioxidative Effects of Ginger and Cinnamon: A Comprehensive Review of Evidence and Molecular Mechanisms Involved in Polycystic Ovary Syndrome (PCOS) and Other Oxidative Stress-Related Disorders
Ginger and cinnamon can help manage PCOS and related disorders by reducing oxidative stress and inflammation.
research Bimatoprost
research RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells
RE-ORGA, a Korean herb extract, may help prevent hair loss.