7 citations
,
January 1981 in “Springer eBooks” Certain small molecules and polymers can change hair's physical properties and how it feels by affecting the bonds within the hair.
February 2026 in “Macromolecular Bioscience” Keratin-based hydrogels with calcium are effective for delivering anti-fibrotic drugs.
47 citations
,
June 1994 in “Experimental Cell Research” mHa2 and mHa3 keratins have different structures and roles in mouse hair and tongue tissues.
68 citations
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August 2014 in “PeerJ” Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
January 1999 in “Journal of Investigative Dermatology” March 2026 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” The scaffold improves wound healing and tissue regeneration.
40 citations
,
March 1991 in “Journal of Investigative Dermatology” 39 citations
,
June 2012 in “Journal of Structural Biology” Disulfide bonds are crucial for hair structure during keratinization.
69 citations
,
October 2013 in “Tissue Engineering Part A” Keratin hydrogel improves nerve regeneration and motor recovery.
December 2022 in “Deleted Journal” Sheep wool keratin solution safely and effectively promotes hair growth.
101 citations
,
August 2001 in “The Journal of Cell Biology” A new keratin 6 type in mice explains why some mice without certain keratin genes still have normal hair and nails.
4 citations
,
January 2015 in “Sen'i Gakkaishi” Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.
12 citations
,
January 2018 in “Biomaterials Science” Softer hydrogel surfaces help maintain hair growth-related functions in skin cells.
8 citations
,
February 2025 in “Frontiers in Medicine” IGF-1, KGF, and stem cells help skin cells move and survive, potentially speeding up wound healing.
14 citations
,
May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
49 citations
,
January 2017 in “Journal of Materials Chemistry B” The hydrogel helps heal skin injuries by promoting blood vessel and hair growth.
5 citations
,
October 2002 in “PubMed” Human hair keratin scaffolds help repair injured muscles by breaking down and activating muscle cell growth.
March 2023 in “Frontiers in Cell and Developmental Biology” Proteoglycans are vital for tissue growth and healing, with potential as treatment targets.
89 citations
,
April 2015 in “Materials Science and Engineering C” Keratin-based hydrogels from human hair improve wound healing effectively.
150 citations
,
August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
29 citations
,
July 2015 in “Journal of Medical Genetics” A genetic variant in the KRT25 gene causes tightly curled hair.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.
8 citations
,
May 2020 in “International journal of biological macromolecules” Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
11 citations
,
April 2022 in “Biophysical Journal” Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.
2 citations
,
December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
10 citations
,
November 2016 in “International Journal of Cosmetic Science” A tough membrane between the outer and inner layers of human hair protects it from damage.
93 citations
,
July 2006 in “Journal of Investigative Dermatology” K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.
53 citations
,
September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
133 citations
,
June 1993 in “Molecular and Cellular Biology” The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.