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The guideline emphasizes a multidisciplinary approach and informed consent for gender-affirming hormone treatment, with regular follow-ups and individualized care.

Hox genes are crucial for development and tissue maintenance, affecting structures and functions throughout life.

GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.

Leydig cell tumors can cause high testosterone and symptoms in postmenopausal women, and removing them improves symptoms.

A woman's increased facial hair and hair loss were caused by a rare ovarian tumor, cured by surgery.

Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.

Leydig cell tumors can cause high testosterone in women and are treated by removing the ovaries.

Androgens affect many aspects of female health, and more research is needed to understand their roles and treatment potential.

Thorough evaluation and surgery are crucial for managing rare ovarian tumors in postmenopausal women with high androgen levels.

Bilateral salpingo-oophorectomy resolved hyperandrogenism in a postmenopausal woman with rare ovarian tumors.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

A rare, non-cancerous ovarian tumor was successfully treated with surgery, improving the patient's symptoms.

A new gel helps grow mature eggs in a lab that can be fertilized and develop further.

Androgens affect the function and health of the endometrium.

Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Notch signaling is crucial for specifying niche cells in Drosophila testis.

DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.

Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.

An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.

circCFAP20DC helps goat ovarian cells grow, aiding follicle development.

Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.

A rare ovarian tumor caused high testosterone in a postmenopausal woman, resolved by surgery.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.