January 2024 in “International Journal of Trichology” Human platelet-rich plasma is better than fetal bovine serum for growing cells that help hair regrow.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
August 2023 in “European Journal of Plastic Surgery” 3D bioprinting is advancing in plastic and reconstructive surgery, especially for creating tissues and improving surgical planning, but faces challenges like vascularization and material development.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
July 2023 in “International journal of trichology” Platelet-rich Plasma (PRP) helps treat hair loss effectively, especially when prepared using the double-spin method.
June 2023 in “Journal of Cosmetic Dermatology” The treatment combining platelet-rich plasma and a non-cross-linked hyaluronic acid compound significantly improved hair density and reduced bald areas in women with androgenetic alopecia, and it's safe with only mild side effects.
December 2021 in “Journal of clinical images and medical case reports” PRP generally shows better results for hair regrowth than mesotherapy, but more research is needed.
February 2018 in “InTech eBooks” PRP therapy is effective for hair regrowth and improving hair quality with minimal side effects.
Injecting a person's own skin cells back into their skin is a promising, safe, and affordable treatment for skin disorders.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
May 2015 in “Hair transplant forum international” The article concludes that PRP might help with hair loss, but more detailed research is necessary.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
418 citations
,
January 2018 in “Journal of Investigative Dermatology” Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
216 citations
,
May 2003 in “Journal of Investigative Dermatology” Glycerol is essential for skin hydration in mice without sebaceous glands.
179 citations
,
June 2000 in “The American journal of pathology” The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.
164 citations
,
February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
118 citations
,
April 2020 in “Stem Cell Research & Therapy” IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.
115 citations
,
August 2020 in “International Journal of Molecular Sciences” A PRP concentration of 1.0 × 10^6 plt/μL is best for tissue repair.
102 citations
,
April 2014 in “PloS one” Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
99 citations
,
September 2007 in “The American journal of pathology” Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
93 citations
,
May 2002 in “Journal of Investigative Dermatology” Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.
90 citations
,
July 2020 in “Stem Cell Research & Therapy” Stem cell vesicles can reduce skin aging from UVB by lowering inflammation and oxidative stress.
67 citations
,
September 2017 in “Cell Reports” Caloric restriction improves skin and fur structure but can cause muscle loss and movement issues.
65 citations
,
March 2004 in “Journal of Clinical Investigation” Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
64 citations
,
March 2004 in “Journal of Clinical Investigation” Targeting ornithine decarboxylase can help prevent skin cancer.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
60 citations
,
December 2020 in “Stem Cell Research & Therapy” ASC-CM is more effective than EV for treating osteoarthritis.
56 citations
,
November 2003 in “Journal of Investigative Dermatology” MMP-19 may worsen skin diseases by affecting skin growth and inflammation.