5 citations
,
February 2022 in “International Journal of Molecular Sciences” Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
January 2024 in “Cosmetics” HAIR & SCALP COMPLEX may help treat hair loss by stimulating hair growth and restarting the hair cycle.
118 citations
,
April 2020 in “Stem Cell Research & Therapy” IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.
55 citations
,
April 2022 in “Journal of Molecular Medicine” Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
3 citations
,
August 2025 in “Stem Cell Research & Therapy” Adipose-derived stem cells show promise in treating hair loss by promoting hair regrowth and improving hair follicle function.
10 citations
,
August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
10 citations
,
May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
4 citations
,
June 2025 in “Frontiers in Immunology” BAFF-targeted therapies can reduce autoimmune disease activity, but more research is needed for precise treatments.
24 citations
,
September 2005 in “Journal of Cellular Biochemistry” Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
December 2025 in “Frontiers in Immunology” Restoring nerve-macrophage communication may help treat autoimmune diseases.
April 2024 in “Dermatovenerologiâ, kosmetologiâ” Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires various treatments to prevent this.
April 2024 in “Dermatovenerologiâ, kosmetologiâ” Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires treatment to prevent malignancy.
August 2022 in “Research Square (Research Square)” Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
12 citations
,
September 2021 in “The International Journal of Developmental Biology” Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.
8 citations
,
February 2025 in “Frontiers in Medicine” IGF-1, KGF, and stem cells help skin cells move and survive, potentially speeding up wound healing.
9 citations
,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
6 citations
,
April 2025 in “Plastic and Aesthetic Research” Biomaterial characteristics can influence macrophages to promote healing and improve tissue regeneration.
January 2026 in “Frontiers in Immunology” Icariin can regulate macrophages and may help treat inflammation, cancer, bone disorders, and fibrotic diseases.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
19 citations
,
November 2011 Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
55 citations
,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
47 citations
,
March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
520 citations
,
January 2017 in “AIMS biophysics” Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
70 citations
,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
65 citations
,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
51 citations
,
March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
8 citations
,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
7 citations
,
January 2009 in “Biological & pharmaceutical bulletin” Ferrous Ferric Chloride may improve skin cell function and increase hair growth in mice.