September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
September 2021 in “CRC Press eBooks” Lichen planopilaris causes permanent hair loss and scarring due to damage to hair follicles and can be mistaken for other hair loss conditions.
4 citations
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July 2019 in “IOP conference series” Most young men with early gray hair have low vitamin D but normal iron levels.
April 2025 in “Turkish Journal of Hematology” Nilotinib may cause gray hair to return to its original color.
1 citations
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December 2017 in “The Medical journal of Basrah University” People with metabolic syndrome get gray hair earlier.
May 2023 in “Authorea (Authorea)” Levofloxacin may cause skin discoloration and hair loss as side effects.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
62 citations
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December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
June 1937 in “Science news-letter/Science news letter” Vitamin B can prevent hair from turning gray in rats.
17 citations
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January 2015 in “Pharmacognosy Research” A herbal mix, especially with Jatamansi, effectively darkens gray hair.
March 2015 in “Journal of Visualized Experiments” A new method measures mouse hair loss using shades of gray.
7 citations
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December 2018 in “Journal of Cosmetic Dermatology” Eating vegetarian, having allergies, and family history might be linked to getting gray hair early.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
April 2023 in “Journal of Investigative Dermatology” Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
13 citations
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September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
260 citations
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January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
23 citations
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November 2007 in “Actas Dermo-Sifiliográficas” Thyroid hormone (T3) may reverse gray hair by stimulating hair growth.
July 2025 in “Pigment International” Follicular vitiligo causes hair to gray without skin color loss.
June 2026 in “Quality in Sport” Premature hair graying has many causes, but no cure yet.
19 citations
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January 2015 in “Skin appendage disorders” The report found a new type of hair loss in African-American women that affects more areas of the scalp than previously thought.
15 citations
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August 2014 in “Journal of dermatological science” Pueraria thunbergiana extract may help prevent hair from turning gray.
6 citations
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January 2019 in “Indian Journal of Pharmacology” Melitane 5% and hair supplements improved hair color in a 14-year-old with early graying.
13 citations
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January 2012 in “Dermatology” Eruptive vellus hair cysts are rare, benign skin lesions that are hard to treat.
8 citations
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November 2019 in “Journal of Trace Elements in Medicine and Biology” Higher hair iron levels are linked to changes in brain structure and function.
77 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
11 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
1 citations
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October 2023 in “Skin Research and Technology” Hair sunscreens were less effective than expected, especially for dark hair.
Premature hair graying is common and linked to stress, obesity, vitamin deficiencies, family history, lack of exercise, smoking, and allergies.
January 2012 in “Journal of the Dermatology Nurses’ Association” The document explains hair growth, hair loss types, and other hair-related terms.