research Endocrinological evaluation and hormonal therapy for women with difficult acne
Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
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research THE GLOBAL CHALLENGE OF CHEMOTHERAPY TOXICITY: RETHINKING SUPPORTIVE CARE IN MODERN ONCOLOGY
Better supportive care is needed to manage chemotherapy side effects.
research Genome-wide shifts in gene expression induced in theca-interstitial cells by inflammatory stimuli
African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.
research Hallmark evidence of lipopolysaccharide (LPS) tolerance in obese women with polycystic ovary syndrome (PCOS) - LPS-induced NFkB suppression in mononuclear cells (MNC) is linked to hyperandrogenism in PCOS
High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.
research Potential role and therapeutic interests of myo-inositol in metabolic diseases
Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
research The Rotterdam Study: 2018 update on objectives, design and main results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Defective trophoblast function in mice with a targeted mutation of Ets2
Ets2 gene is crucial for placental development in mice.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research The diagnosis and treatment of iron deficiency and its potential relationship to hair loss
Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.
research Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin
Hair follicle development and microbes help regulatory T cells gather in newborn skin.
research COVID-19 and Sex Differences
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Zinc Therapy in Dermatology: A Review
Zinc is effective for treating various skin conditions, including warts and acne.
research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice.
TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
research A Perspective on RNAi-Based Biopesticides
RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
research Feather arrays are patterned by interacting signalling and cell density waves
Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity
Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
research From causes of aging to death from COVID-19
Older age and related diseases increase COVID-19 risk, but anti-aging treatments might help.
research Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility
Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
research Foxp3 Post-translational Modifications and Treg Suppressive Activity
Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
research Olfactory receptor OR2AT4 regulates human hair growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research Androgen excess: Investigations and management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.