research Spatiotemporal Labeling of Melanocytes in Mice
The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
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research Biology of melanocytes in mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis
Immune cells boost stem cell activity in hairy moles, causing more hair growth.
research ABSENCE OF H2O2 BREAKDOWN IN HUMAN HAIR MEDULLA IMPLICATIONS IN FOLLICULAR MELANOGENESIS
Human hair medulla doesn't break down hydrogen peroxide, which may affect hair color formation.
research 1229 Melanocyte cell states defined and visualized in developing mouse skin
Researchers found three types of melanocytes in developing mouse skin, each with different genes and locations.
research Inflammatory and non-melanocytic tumoral pathology of the nail
The document concludes that understanding nail anatomy is key for diagnosing nail diseases, early signs of nail melanoma may allow for less aggressive treatment, and specific genetic mutations are important in thyroid cancer prognosis and treatment.
research Hair development and Langerhans cell migration during human embryogenesis
Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
research Somatic mutations distinguish melanocyte subpopulations in human skin
Hair follicles protect melanocytes from sun damage, helping them replenish skin.
research Detection of Functionally Active Melanocortin Receptors and Evidence for an Immunoregulatory Activity of α-Melanocyte-Stimulating Hormone in Human Dermal Papilla Cells
αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.
research The Psychology of Gray Hair
Stress can cause hair to turn gray by depleting pigment-producing cells through the release of a stress hormone.
research Untersuchungen der Fremdstoffbindung in permanenten Keratinozyten- und Melanozyten-Zelllinien sowie die Eignung von Primärkulturen aus humanen Haarfollikeln zur In-vitro-Messung der Fremdstoffaufnahme im Haar
Unpigmented keratinocytes absorb substances faster, while melanocytes bind more strongly to melanin.
research Melanocytes: The new Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
research Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses
Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
research Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.
research From neural crest cells to melanocytes: cellular plasticity during development and beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Hair Biology
The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
research Anatomy and Physiology of Hair
Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
research Wnt/β-catenin signaling promotes aging-associated hair graying in mice
A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
research Stem Cells of the Hair Follicular Tissue: Application in Cell Based Therapy for Vitiligo
Hair follicle stem cells could be used to treat the skin condition vitiligo.
research Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro
The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
research Immunohistochemical assessment of SOX10 and its relation to the immune cellular infiltrate in alopecia areata follicles
SOX10 in hair follicles is linked to inflammation in alopecia areata.
research Melan-A Positive cells significantly expressed in immune-targeted follicles of Alopecia Areata
Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
research Hair Changes Caused by Aging
Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
research Runx3 is involved in hair shape determination
Runx3 helps determine hair shape.
research CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth
Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
research SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling
SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
research Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo
New mouse models help study melanocytic cells for melanoma research.
research Androgens and hair growth
Androgens can both increase and decrease hair growth in different parts of the body.