2 citations
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April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
1 citations
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April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
1 citations
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April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
1 citations
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March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Biodegradable scaffolds help regenerate wounds and hair by activating the immune system.
1 citations
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October 2015 in “CRC Press eBooks” PRP and stem cells can help treat baldness by promoting hair growth.
June 2026 in “Materials Today Communications” The hydrogel speeds up wound healing with electrical stimulation.
October 2025 in “Journal of Nanobiotechnology” The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.
September 2025 in “International Journal of Biological Macromolecules” The new hydrogel with curcumin speeds up wound healing safely and effectively.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
March 2022 in “Research Square (Research Square)” 4-aminopyridine, a FDA-approved drug, speeds up skin wound healing and tissue regeneration.
November 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” 4-aminopyridine helps skin wounds heal faster and better.
Using a combination of AMD3100 and FK506 can speed up and improve wound healing in diabetic rats.
April 2016 in “Journal of Investigative Dermatology” Full thickness wounds on Lanyu pigs' skin resulted in abnormal skin structure and function due to changes in molecular expression patterns.
January 2012 in “Journal of Investigative Dermatology” Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
128 citations
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August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
66 citations
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May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
7 citations
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November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
1 citations
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June 2013 in “Science-business Exchange” Increasing the levels of a protein called FGF9 can promote hair growth, but humans may not respond the same way due to a lack of certain cells.
February 2024 in “Frontiers in physiology” Modifying certain signals in the body can help wounds heal without scars and regrow hair.
9 citations
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December 2002 in “Novartis Foundation Symposium” LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
9 citations
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January 1998 in “Studia Anglica Posnaniensia: international review of English Studies” Wound-induced hair growth may help study regeneration and aging, but it's unclear if this ability decreases with age.
April 2015 in “Plastic and Reconstructive Surgery” Activating TLR3 helps improve skin and hair follicle regeneration after wounds.
April 2015 in “Plastic and Reconstructive Surgery” TLR3 activation helps improve skin and hair follicle healing in mice.
May 2012 in “Scientific American” New app improves storm surge predictions; advances in baldness treatment show potential but require time.
May 2012 in “Scientific American” Blocking a compound called prostaglandin D₂ might help treat hair loss.
4 citations
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October 2021 in “Journal of Cellular and Molecular Medicine” White blood cells and their traps can slow down the process of new hair growth after a wound.
July 2025 in “ACS Applied Materials & Interfaces” Ultrasound-activated gel with stem cell vesicles improves skin healing and regeneration.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Ultrasound and GelMA hydrogel with stem cell vesicles improve skin healing and regeneration.
Hair follicles supply a crucial brain development protein to the brain via platelets.