314 citations
,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
February 2021 in “Journal of The American Academy of Dermatology” Fibrosis in the bulge area of hair follicles can cause hair thinning in male pattern baldness, and drugs that inhibit fibrosis might help reverse this.
64 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
25 citations
,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
1 citations
,
March 2019 in “International Journal of Molecular Medicine” Mouse hair follicle cells can become heart-like cells without genetic changes.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
53 citations
,
February 2015 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is essential for normal hair growth and preventing hair loss.
414 citations
,
August 2005 in “Nature” Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.
294 citations
,
February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
56 citations
,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
5 citations
,
January 2019 in “Methods in molecular biology” Multiphoton microscopy can effectively image live cells in cornea, skin, and hair follicles over time.
4 citations
,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
1 citations
,
January 2022 in “Cell Biology International” Changing CDK4 levels affects the number of stem cells in mouse hair follicles.
1 citations
,
December 2021 in “Development & Reproduction” Lack of FPR2 slows hair growth by affecting hair cell activity.
Vegan exosome-like vesicles from microalgae improve skin and hair health, reducing wrinkles and enhancing elasticity.
August 2024 in “Cell Death and Disease” Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
April 2023 in “Journal of Investigative Dermatology” The research found that certain factors in hair follicle cells control hair growth and development, and these could be used to create new treatments for hair loss.
June 2022 in “Pflügers Archiv - European Journal of Physiology” The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.
January 2022 in “SSRN Electronic Journal” Mouse hair follicles age, causing more white hairs due to fewer pigment stem cells.
August 2013 in “eCommons (Cornell University)” Runx1 and CDK inhibitors help keep hair follicle stem cells inactive, affecting their future roles.
Senescence and genomic instability in fibroblasts contribute to hair loss and impaired skin regeneration with age.
September 2022 in “Journal of Theoretical Biology” Hair follicles can regenerate after radiation damage but not during a specific growth phase.
January 2023 in “Figshare” Mouse skin and hair aging starts at 200 days, with changes in hair follicles and more white hairs as signs of aging.
211 citations
,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
165 citations
,
December 2004 in “Differentiation” BMP signaling is crucial for skin and hair growth.
161 citations
,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
85 citations
,
January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
85 citations
,
June 2017 in “Journal of Investigative Dermatology” Blimp1 is crucial for hair follicle growth and skin health.
68 citations
,
April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.