37 citations
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April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
27 citations
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August 2003 in “Anais Brasileiros de Dermatologia” Neuropeptides affect skin inflammation, repair, and hair growth, with potential for therapy.
22 citations
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January 2010 in “Humana Press eBooks” The vitamin D receptor can affect gene activity even without its usual hormone in hair and skin.
16 citations
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August 1989 in “Human Reproduction” Hirsutism in females is caused by high male hormones or sensitive hair follicles.
9 citations
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January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.
5 citations
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November 2005 Confocal Laser Scanning Microscopy is effective for tracking compounds in the skin.
4 citations
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January 2014 in “BioMed Research International” Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.
2 citations
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September 2025 in “Future Journal of Pharmaceutical Sciences” Lupeol shows promise for hair growth but needs better absorption and safety testing.
1 citations
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March 2025 in “Frontiers in Physiology” Methotrexate, resveratrol, and curcumin may help treat alopecia areata by targeting immune cells.
1 citations
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October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
1 citations
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January 2013 in “MedChemComm” PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Androgenetic alopecia is common hair loss caused by genetics and hormones, with treatments to slow it but no cure.
May 2026 in “Journal of Human Immunity” Ruxolitinib reduced inflammation and improved symptoms in APECED patients but may cause anemia and weight gain.
March 2026 in “Mendeley Data” Basement membrane-like ECM supports fibroblast aggregation and cohesion.
A coordinated approach combining medical, trichological, and visual support is needed to better manage hair loss.
February 2026 in “Middle European Scientific Bulletin” Improving scalp microbiome may help restore hair and improve scalp health.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Chronic stress can cause hair loss, but relaxation and gentle care can help manage it.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Chronic stress can cause hair loss, but relaxation and gentle care can help manage it.
January 2026 in “Ife Journal of Science” Rosemary extract may help treat hair loss.
January 2026 in “Dermatology Review” Androgenetic alopecia, the most common hair loss disorder, involves follicle miniaturization due to genetic and androgen interactions, particularly dihydrotestosterone. While not life-threatening, it can significantly impact quality of life. Early diagnosis is crucial for slowing progression and personalizing treatment. Established treatments include topical minoxidil and oral 5a-reductase inhibitors like finasteride. Other options, such as topical finasteride, low-level laser therapy, and hair transplantation, depend on severity and availability. Emerging treatments like low-dose oral minoxidil, platelet-rich plasma, and microneedling show promise, but require more evidence for long-term efficacy and safety.
December 2025 in “Biomolecules” Targeting protein S-palmitoylation could lead to new skin disease treatments.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
January 2025 in “Cellular and Molecular Life Sciences” BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
April 2024 in “Journal of biomedical and pharmaceutical research” Nanoparticles offer significant benefits over traditional chemotherapy for cancer treatment.
February 2024 in “Cosmoderma” Low-dose oral minoxidil can help treat male and female pattern hair loss, especially in those who can't use topical treatments or have heart health issues.
February 2024 in “International journal of molecular sciences” Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.
August 2023 in “Journal of Investigative Dermatology” Skin organoids can regenerate hair by forming specific cell units with certain signals.
June 2023 in “Buletin de psihiatrie integrativă” Alopecia causes significant emotional distress and psychological issues, requiring combined skin and mental health treatment.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” GATA6 is important for maintaining and differentiating cells in a key area of human skin.
October 1996 in “Dermatologic Clinics” Research on hair disorders has advanced, with promising future progress in understanding and treating these conditions.