September 2016 in “Journal of Dermatological Science” Hair follicle stem cells can become heart muscle cells.
55 citations
,
November 2010 in “Development” Hair follicles in mutant mice self-organize into ordered patterns within a week.
98 citations
,
May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
61 citations
,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
19 citations
,
July 2020 in “EBioMedicine” A gene variant increases the risk of a type of hair loss by affecting hair protein production.
8 citations
,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
1 citations
,
September 2023 in “Animals” A new goat gene affects cashmere fiber thickness; certain variations can make the fibers coarser.
October 2024 in “BMC Genomics” Understanding hair follicle development can help improve cashmere quality.
A genetic variant in the KRT71 gene may cause loose anagen hair and wooly hair, and symptoms might improve with age.
286 citations
,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
91 citations
,
December 2006 in “Proceedings of the National Academy of Sciences” Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.
50 citations
,
January 1986 44 citations
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May 1997 in “Journal of Biological Chemistry” The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
41 citations
,
September 2003 in “Journal of Investigative Dermatology” Overexpression of COX-2 causes early hair loss in mice, but can be prevented with a COX-2 inhibitor.
33 citations
,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
22 citations
,
September 2001 in “Journal of Investigative Dermatology” S100A8 and S100A9 proteins help form hair shafts during growth.
18 citations
,
August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
18 citations
,
June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
16 citations
,
September 2020 in “Animals” circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.
12 citations
,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
1 citations
,
February 2023 in “Journal of Natural Fibers” Higher keratin protein levels are important for the wool's shine in Magra sheep.
1 citations
,
June 2021 in “Biomolecules & Therapeutics” Activating δ-opioid receptors can help hair grow.
March 2026 in “Virulence” Vimentin and keratin help viruses spread and could be targets for antiviral treatments.
August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
March 2025 in “International Journal of Molecular Sciences” The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.
May 2024 in “Molecules/Molecules online/Molecules annual” Plant extracts can help prevent hair loss and promote hair growth.
March 2024 in “International journal of molecular sciences” The research identified key proteins that affect wool fiber thickness in Angora rabbits.
January 2024 in “Inflammation and regeneration” Th22 cells are essential for Tβ15-induced hair growth in mice.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
1 citations
,
November 2023 in “Chemical and Biological Technologies in Agriculture” JUNB boosts hair growth in goats by helping specific skin cells multiply.