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GlossaryHair Multiplication

replicating hair follicle cells to treat hair loss

Hair Multiplication, also known as hair cloning, is a technique aimed at treating hair loss by replicating hair follicle cells. In this process, healthy hair follicles are extracted, cultured in a lab to multiply the cells, and then re-implanted into the scalp to promote new hair growth. This method holds promise for providing a more abundant and sustainable solution for individuals suffering from conditions like androgenetic alopecia.

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Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

136 citations , May 2019 in “Cells”

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

research Hair follicular cell/organ culture in tissue engineering and regenerative medicine

21 citations , October 2009 in “Biochemical Engineering Journal”

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

research Faculty Opinions recommendation of Application of mesenchymal stem cells derived from bone marrow and umbilical cord in human hair multiplication.

November 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Mesenchymal stem cells from bone marrow and umbilical cord can help regenerate hair follicles.

research Protocolo terapéutico de la alopecia

February 2018 in “Medicine - Programa De Formación Médica Continuada Acreditado”

Minoxidil and finasteride are the main FDA-approved treatments for hair loss, with other methods showing promise but lacking strong evidence.

research An exclusive review of melatonin effects on mammalian melanocytes and melanoma

3 citations , November 2022 in “Experimental dermatology”

Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.

Promotion of Anagen, Increased Hair Density, and Reduction of Hair Fall in a Clinical Setting Following Identification of FGF5-Inhibiting Compounds via a Novel 2-Stage Process

research Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process

27 citations , February 2017 in “Clinical, Cosmetic and Investigational Dermatology”

New compounds were found to help increase hair growth and decrease hair loss.

research Androgens and androgen receptor action in skin and hair follicles

100 citations , September 2017 in “Molecular and Cellular Endocrinology”

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

research The Effects of Smoking on Hair Health: A Systematic Review

5 citations , January 2021 in “Skin appendage disorders”

Smoking is linked to more hair loss and premature graying compared to nonsmokers.

research Cell-based treatments for hair loss: research update on “hair cloning”

2 citations , March 2013 in “Hair transplant forum international”

Research on "hair cloning" for hair loss shows potential for hair thickening but has not yet achieved new hair growth in humans.

research Hair Growth Effect of Emulsion Extracted Brevilin A, a JAK3 Inhibitor, from Centipeda minima

15 citations , June 2020 in “Processes”

CMX from Centipeda minima can significantly improve hair growth in mild to moderate balding.

The Use of Stem Cell Differentiation Stage Factors Taken from Zebrafish Embryos During Organogenesis and Their Role in Regulating Gene Expression of Normal and Pathological Cells

research The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells

3 citations , July 2020 in “International Journal of Molecular Sciences”

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

research Current Status of the Applications of Conditioned Media Derived from Mesenchymal Stem Cells for Regenerative Medicine

3 citations , January 2023 in “Physiological Research”

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

research A Platform for Determining Medicinal Plants with Targeted 17β-Hydroxysteroid Dehydrogenase Modulation for Possible Hair Loss Prevention

February 2024 in “Cosmetics”

The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia

4 citations , March 2022 in “Pharmaceutics”

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

Regenerative Medicine Applications in Dermatology and Aesthetics

research Regenerative medicine in aesthetics

2 citations , June 2022 in “Cosmoderma”

Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.

research Finasteride-its impact on sexual function and prostate cancer

33 citations , January 2009 in “Journal of Cutaneous and Aesthetic Surgery”

Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.

research Alcohol and Prostate Cancer: Time to Draw Conclusions

9 citations , February 2022 in “Biomolecules”

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Moving Beyond Boundaries: Utilization of Longitudinal Exposure–Response Model for Bounded Outcome Score to Inform Decision Making in the Accelerated Drug Development Paradigm

research Moving Beyond Boundaries: Utilization of Longitudinal Exposure–Response Model for Bounded Outcome Score to Inform Decision Making in the Accelerated Drug Development Paradigm

5 citations , February 2024 in “Clinical Pharmacokinetics”

A 50 mg daily dose of ritlecitinib is effective for alopecia areata, with temporary treatment breaks up to 6 weeks not affecting results.

research Natural Sources of Therapeutic Agents Used in Skin Conditions

35 citations , April 2024 in “Life”

Bee venom, fig, and geranium oil can effectively treat skin conditions and are safer alternatives to some conventional drugs.

research Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering

57 citations , February 2013 in “Journal of Dermatological Science”

Improving the environment and cell interactions is key for creating human hair in the lab.

research Hair physiology and its disorders

31 citations , May 2008 in “Drug Discovery Today: Disease Mechanisms”

Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.

research Hair follicles and their role in skin health

16 citations , December 2006 in “Expert Review of Dermatology”

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

research Dental derived stem cell conditioned media for hair growth stimulation

15 citations , May 2019 in “PLOS ONE”

Substances from dental stem cells might help treat hair loss.

research 3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration

February 2025 in “Theranostics”

3D bioprinting with special hydrogels can create artificial skin that heals wounds and regrows hair in mice.