research Lgr5 marks cycling, yet long-lived, hair follicle stem cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
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research Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research The Hair Follicle as a Dynamic Miniorgan
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research The secret life of the hair follicle
Hair follicles create different cell layers and proteins, controlled by various molecules.
research Measurement of cortisol in human Hair as a biomarker of systemic exposure
Hair cortisol can be used to measure long-term stress exposure.
research Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34
CD34 is a marker for isolating stem-like cells in mouse hair follicles.
research Growth of the Hair
Hair growth is cyclic and influenced mainly by local factors.
research Control of hair growth and follicle size by VEGF-mediated angiogenesis
VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
research Hair as a retrospective calendar of cortisol production—Increased cortisol incorporation into hair in the third trimester of pregnancy
Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol
Human hair follicles can produce cortisol like the body's stress response system.
research Molecular principles of hair follicle induction and morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Hair Follicle Pigmentation
Hair color is determined by melanin produced and transferred in hair follicles.
research Hair-bearing human skin generated entirely from pluripotent stem cells
Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
research Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons
Hair-follicle stem cells can become neurons.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Conditional telomerase induction causes proliferation of hair follicle stem cells
Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.
research Variations of Hair Follicle Size and Distribution in Different Body Sites
Hair follicle size and distribution vary significantly across different body sites.
research Minoxidil: mechanisms of action on hair growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells
Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
research Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge
The K15 promoter effectively targets stem cells in the hair follicle bulge.
research The hair cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
research Nestin expression in hair follicle sheath progenitor cells
Nestin is found in hair follicle progenitor cells, linking them to neural stem cells.
research Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles
Human hair follicles can provide stem cells for regenerative medicine.
research Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Sox2-positive cells determine specific hair follicle types in mammals.
research Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells
SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.