16 citations
,
April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
31 citations
,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
6 citations
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February 2010 in “Biotechnology and bioprocess engineering” Using umbilical cord stem cells can help create hair-growing tissues more affordably.
158 citations
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May 2003 in “Journal of Investigative Dermatology” Hair growth is influenced by dynamic changes in hair follicle cells, which could help treat hair loss.
22 citations
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June 2024 in “Cell” Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.
3 citations
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June 2021 in “PLOS ONE” A topical BRAF inhibitor, vemurafenib, can speed up wound healing and promote hair growth, especially in diabetic patients.
425 citations
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June 2020 in “Nature” Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
192 citations
,
January 2018 in “Burns & Trauma” Current skin substitutes help heal severe burns but don't fully replicate natural skin features.
October 2025 in “Cell Transplantation” New hair loss treatments like stem cells and gene therapy show promise but need more research for safety and effectiveness.
April 2015 in “MOJ Cell Science & Report” Rat hair follicle stem cells can be used to improve blood vessel growth in engineered skin.
61 citations
,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
380 citations
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March 2000 in “Proceedings of the National Academy of Sciences” Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
333 citations
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March 2000 in “Proceedings of the National Academy of Sciences” Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
70 citations
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April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.
45 citations
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December 2007 in “The FASEB journal” There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
39 citations
,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
4 citations
,
September 2024 in “Cell Reports” Granulocyte colony stimulating factor helps heal wounds without scars.
October 2025 in “Advanced Healthcare Materials” The hydrogels improve wound healing and tissue regeneration better than traditional treatments.
September 2025 in “Development” Nelfb is crucial for forming skin fat tissue by regulating genes needed for fat cell development.
April 2024 in “The Journal of experimental medicine/The journal of experimental medicine” Treg cells help repair and regenerate tissues by interacting with local cells.
July 2025 in “Bioactive Materials” New engineering methods show promise for regenerating hair follicles using stem cells and advanced technologies.
August 2025 in “Plastic and Aesthetic Research” Microneedling can effectively treat hair loss and works well with other treatments, but more research is needed.
31 citations
,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
October 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
February 2025 in “Stem Cell Research & Therapy” Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
51 citations
,
January 2024 in “Burns & Trauma” Engineered extracellular vesicles can improve tissue repair and regeneration.
40 citations
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April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
9 citations
,
March 2022 in “Frontiers in Immunology” Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
2 citations
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May 2023 in “Veterinary Pathology” Understanding genetic variations in mice is crucial for studying skin, hair, or nail abnormalities.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.