December 2023 in “Clinical, cosmetic and investigational dermatology” The study found that white hair in vitiligo has specific patterns and structures, which vary with the stage of the disease and may be similar to another hair condition.
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
March 2019 in “SLAS TECHNOLOGY” New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
101 citations
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December 2014 in “Stem Cells and Cloning Advances and Applications” Oral stem cells show promise for tissue repair, but more human trials are needed.
8 citations
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August 2019 in “ACR Open Rheumatology” Defective repair processes may cause immune activation and inflammation in psoriatic disease.
5 citations
,
June 2025 in “Journal of Functional Biomaterials” 3D bioprinting offers new ways to treat head and neck defects with bioinks that mimic natural tissues.
2 citations
,
November 2024 in “ACS Omega” Snail secretion-loaded dressings can improve skin regeneration and wound healing.
April 2017 in “Al-Azhar Medical Journal” PRP is an effective and safe treatment for alopecia areata.
1 citations
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January 2007 in “AIP conference proceedings” High-resolution x-ray images showed three main structures in human hair: medulla, cortex, and cuticle.
4 citations
,
August 2024 in “Health Science Reports” Hair follicle punch grafts effectively help heal difficult wounds with few complications.
5 citations
,
April 2025 in “Journal of Functional Biomaterials” A-PRF+ improves bone healing and stability in oral surgery.
70 citations
,
August 2019 in “European Journal of Medicinal Chemistry” 1 citations
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September 2022 Sugar waxing slows hair growth and reduces thickness but can cause more ingrown hairs and inflammation than hard waxing.
1 citations
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January 2017 in “Indian Journal of Dermatology Venereology and Leprology” Hard water increases magnesium deposits on hair without changing its structure.
March 2025 in “INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT” Hair health is influenced by genetics, lifestyle, and modern treatments, but practical solutions are limited.
The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.
71 citations
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November 2009 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
51 citations
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February 2004 in “Environmental Health Perspectives” Control variability makes it hard to confirm low-dose endocrine effects.
51 citations
,
April 1982 in “Lancet” Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
32 citations
,
July 2001 in “Journal of the American Academy of Dermatology” SLHA can be hard to diagnose and needs teamwork between specialists.
23 citations
,
December 2001 in “Lasers in Surgery and Medicine” Permanent hair removal is hard, but using longer laser pulses at lower power might improve results.
21 citations
,
May 2021 in “Patient education and counseling” Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.
21 citations
,
September 2011 in “PubMed” Scalp hair folliculitis is hard to diagnose and treat due to various causes and complex classification.
18 citations
,
October 2016 in “Clinics in Dermatology” The document talks about hard-to-treat and rare acne types, their connection with other health issues, the importance of correct diagnosis, and the challenges in managing them.
17 citations
,
June 2010 in “Journal of Cosmetic Dermatology” Many women with hard-to-treat acne also have PCOS.
15 citations
,
November 2024 in “Pharmaceutics” Peptide drugs now target hard-to-reach proteins more effectively and specifically.
7 citations
,
January 2017 in “International Journal of Trichology” Hair transplant can cause hard-to-treat keloids in some patients.
7 citations
,
July 2004 in “Endocrine practice” Acromegaly can be hard to diagnose in young women with atypical symptoms, and persistent high phosphate levels should lead to growth hormone testing.
6 citations
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July 2015 in “International Journal of Dermatology” Trichoepitheliomas can be hard to distinguish from other skin conditions and often start in teenage years.
6 citations
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May 2007 in “Forensic Science Medicine and Pathology” Minoxidil can make it hard to detect cocaine in hair tests.