January 2026 in “RSC Advances” The hydrogel speeds up diabetic wound healing and reduces scarring.
November 2025 in “Nanoscale Advances” Inorganic nanoparticle-based scaffolds can improve wound healing by fighting bacteria and helping tissue grow.
147 citations
,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
111 citations
,
June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
93 citations
,
June 2011 in “Journal of Neuroscience” p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
68 citations
,
March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
49 citations
,
April 2003 in “Biomaterials” Bismuth subgallate and borneol together improve skin wound healing better than when used separately or compared to other treatments.
9 citations
,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
Plasma-activated water heals diabetic wounds better than other treatments.
July 2025 in “Scientific Reports” RG and RJ gels speed up burn wound healing better than other treatments.
66 citations
,
June 2015 in “Aesthetic Plastic Surgery” Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
23 citations
,
September 2018 in “Journal of Investigative Dermatology” A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.
2 citations
,
November 2023 in “Curēus” Platelet-rich plasma (PRP) speeds up skin wound healing and has potential in medical and cosmetic uses.
2 citations
,
October 2020 in “Drug Discoveries & Therapeutics” Althaea officinalis helps wounds heal faster in rats.
1 citations
,
March 2011 in “Journal of Investigative Dermatology” Blocking RANK signaling might help treat metastatic melanoma, but more research is needed.
January 2026 in “Frontiers in Materials” Metal-organic frameworks help heal wounds by effectively delivering medicine.
July 2025 in “Journal of Research in Pharmacy” Combining Virgin Coconut Oil and Nigella Sativa Oil speeds up healing in diabetic wounds.
280 citations
,
July 2018 in “Antioxidants” Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
83 citations
,
June 2020 in “Materials & Design” Sponge helps heal wounds faster with less inflammation and better skin/hair growth.
23 citations
,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
30 citations
,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
5 citations
,
October 2023 in “Aging” Sonic hedgehog signaling helps heal pressure ulcers by improving blood vessel growth.
March 2025 in “Frontiers in Pharmacology” The hydrogel dressing rapidly heals wounds and promotes blood clotting better than existing options.
13 citations
,
September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
54 citations
,
July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
13 citations
,
January 1963 in “Radiation Research” X-ray microbeams can mimic cosmic rays' effects on tissue, aiding wound healing and hair growth.
January 2026 in “Annals of Clinical Endocrinology and Metabolism” Restoring NAD⁺ may help with aging and chronic diseases, but more research is needed.
71 citations
,
October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
42 citations
,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
18 citations
,
January 2019 in “European journal of histochemistry” Cattle skin has leptin which might control skin and hair growth.