research Gene expression profiling of human keratinocytes exposed to the hair-dying agent, m-aminophenol
m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.
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research Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis
Removing SIX1 in fat cells reduces skin fibrosis.
research Unravelling the link between insulin resistance and androgen excess
AKR1C3 could be a treatment target for metabolic issues in PCOS.
research Costunolide—A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential
Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
research Las alteraciones metabólicas y funcionales asociadas a la COVID-19
Lower LDL-c levels predict higher COVID-19 mortality.
research Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming
Long-term skin biopsy cultures can produce many fibroblasts that remain functional and can be reprogrammed.
research Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control
Hair growth is influenced by dynamic changes in hair follicle cells, which could help treat hair loss.
research Cell type‐specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis
Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis
FOL-026 peptide may help hair growth and cardiovascular health by improving blood flow and cell functions.
research Traditional Chinese medicine derived exosome-like nanovesicles in wound repair and skin regeneration
TCM-derived nanovesicles show promise for wound healing and skin regeneration but need more research.
research Hydroxytyrosol Alleviates Acute Liver Injury by Inhibiting the TNF-α/PI3K/AKT Signaling Pathway via Targeting TNF-α Signaling
Hydroxytyrosol helps reduce liver injury by blocking certain inflammation pathways.
research Matrigel uses in cell biology and for the identification of thymosin β4, a mediator of tissue regeneration
Matrigel supports cell growth and repair, and thymosin beta 4 aids tissue regeneration and healing.
research Microfluidic Technology for the Generation of Cell Spheroids and Their Applications
Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
research In Situ Self-Assembling Liver Spheroids with Synthetic Nanoscaffolds for Preclinical Drug Screening Applications
PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
research Macrophage Related Chronic Inflammation in Non-Healing Wounds
Macrophage issues cause chronic wound inflammation, but therapies can help.
research Advancements and challenges in stem cell transplantation for regenerative medicine
Stem cell transplantation shows promise for treating diseases but faces challenges like safety, ethics, and cost.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin
Integrin α6 helps identify different neural crest cell types in the skin.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrosis and cancer.
research Regulation of stem cell fate by HSPGs: implication in hair follicle cycling
HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
research Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome
Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.
research Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling
FR-1 reduces skin scarring and promotes healing without harmful effects.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
research Emerging biomedical engineering strategies for hair follicle regeneration
New engineering methods show promise for regenerating hair follicles using stem cells and advanced technologies.
research Cellular and molecular mechanisms of repair in acute and chronic wound healing
Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
research Alkylation of human hair keratin for tunable hydrogel erosion and drug delivery in tissue engineering applications
Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
research The Pressurized Skin: A Review on the Pathological Effect of Mechanical Pressure on the Skin from the Cellular Perspective
Understanding how skin cells react to pressure can help diagnose and manage pressure-related skin disorders.