48 citations
,
June 2014 in “Neurobiology of Disease” The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
48 citations
,
June 2013 in “Journal of Dermatological Science” Valproic acid may help hair grow and could be a safe treatment for hair loss.
48 citations
,
September 2011 in “British Journal of Dermatology” Epigenetic changes in blood cells may contribute to alopecia areata.
42 citations
,
July 2007 in “Journal of Biological Chemistry” Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
28 citations
,
May 2015 in “Molecular Neurobiology” LSD1 is crucial for regenerating hair cells in zebrafish.
22 citations
,
January 2017 in “Advanced Healthcare Materials” The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
22 citations
,
April 2010 in “Journal of Cellular Biochemistry” Certain mutations in the hairless protein disrupt its ability to regulate the hair cycle.
21 citations
,
June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
18 citations
,
February 2019 in “Scientific Reports” Trichostatin A helps restore hair-growing ability in skin cells used for hair regeneration.
18 citations
,
October 2009 in “Endocrinology” Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.
17 citations
,
June 2019 in “The journal of immunology/The Journal of immunology” A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
15 citations
,
May 2017 in “Journal of Cellular Biochemistry” The hairless protein is important for skin, hair, and may influence cancer development.
9 citations
,
June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
8 citations
,
August 2023 in “Journal of Investigative Dermatology” Corin speeds up wound healing by helping skin cells move and grow.
6 citations
,
August 2022 in “Science immunology” Foxn1 gene regulation is crucial for thymus development but not for hair growth.
5 citations
,
September 2015 in “PubMed” Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
5 citations
,
September 2011 in “Cell stem cell” Epigenetic changes are crucial for hair follicle stem cells to function properly.
4 citations
,
November 2020 in “BMC Dermatology” Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.
4 citations
,
July 2020 in “Journal of proteomics” Hair protein composition is similar across different races and shapes.
4 citations
,
August 2018 in “Journal of cellular biochemistry” Acid inside cells speeds up aging and turns on aging signs in mice.
3 citations
,
July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model” Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.
2 citations
,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
2 citations
,
January 2015 in “Elsevier eBooks” Epigenetic changes contribute to autoimmune skin diseases.
1 citations
,
July 2021 in “Health & Medical Journal” Men with systemic lupus erythematosus often have more severe symptoms but can respond well to treatment.
1 citations
,
August 2025 in “Epigenetics & Chromatin” H3K4me3 helps control RSPO3 to influence hair growth and development.
June 2026 in “Scholarly review .” Endocrine-disrupting chemicals cause irreversible harm to children's development, increasing disease risk.
June 2026 in “Journal of Biological Studies” Centella asiatica may help extend healthspan by targeting aging processes.
Red light exposure slows aging in mice by improving fat metabolism.
March 2026 in “Animal Models and Experimental Medicine” Gorab deficiency speeds up skin aging by disrupting protein regulation and reducing collagen.
February 2026 in “Advanced Science” Targeting the p300/AR axis may help treat polycystic ovary syndrome.