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New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.

HDMHG0401-10 improves hair loss in men with androgenetic alopecia and has no major side effects.

5α-reductase inhibitors can reduce prostate cancer risk but may increase high-grade tumors, needing more research.

Patients with mycosis fungoides have a higher risk of heart disease.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

New mutations in the VDR gene cause vitamin D-resistant rickets without hair loss.

Taking 5-alpha reductase inhibitors might be linked to breast cancer in men.

Lack of a key enzyme causes severe skin issues and death in mice.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.

Nano selenium and CoQ10 helped reduce blood fat levels and insulin resistance while preventing muscle damage from statin drugs in rats.

Isotretinoin treatment in teens with acne can cause hormonal changes, leading to menstrual irregularity and increased hirsutism.

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.

The HSD3B1 variant increases hair loss risk in overweight women with PCOS.

Antiandrogens and finasteride may help treat excess hair and hair loss in women.

Quercetin and kaempferol may be effective and safe natural treatments for hair loss.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.

Cyproterone acetate is effective for treating hirsutism and acne in women by blocking androgens in the skin and also works as a contraceptive.

5α-reductase inhibitors lower overall prostate cancer risk but not high-grade cancer risk; longer-term screening and new treatments show promise.

Hirsutism affects many women and is managed with a combination of medical treatments and hair removal, tailored to individual needs.

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.