39 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
9 citations
,
June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
5 citations
,
February 2019 in “BioMed Research International” Acne in reproductive-age women may be linked to conditions like PCOS and lifestyle factors, so doctors should check for these when treating acne.
99 citations
,
December 2010 in “Journal of The European Academy of Dermatology and Venereology” The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
63 citations
,
January 2012 in “The European Journal of Contraception & Reproductive Health Care” Some birth control pills have a higher risk of blood clots than others.
59 citations
,
December 2016 in “Clinical, Cosmetic and Investigational Dermatology” Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.
52 citations
,
October 2016 in “Clinics in Dermatology” Some medications can cause acne, and stopping these drugs is the main treatment.
49 citations
,
January 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” RU 58841 may treat acne, hair loss, and excessive hair growth.
46 citations
,
January 2007 in “The European Journal of Contraception & Reproductive Health Care” Birth control pills increase the risk of blood clots, especially within the first year and with certain types.
46 citations
,
August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
43 citations
,
May 1986 in “Clinics in Endocrinology and Metabolism” Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
32 citations
,
October 2003 Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
23 citations
,
October 2015 in “Andrology” New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
22 citations
,
January 2017 in “Dermatology” Spironolactone is effective and safe for treating acne with minimal side effects.
19 citations
,
August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
18 citations
,
August 2011 in “Clinical Drug Investigation” Low-dose isotretinoin combined with pulsed azithromycin cleared acne in most patients, with mild side effects.
11 citations
,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.
10 citations
,
January 2020 in “Advances in Dermatology and Allergology” Lower ghrelin levels and certain gene variations may increase acne risk.
8 citations
,
September 2023 in “Advanced Pharmaceutical Bulletin” Chitosan-coated spironolactone nano carriers effectively treat acne without side effects.
7 citations
,
December 2019 in “American Journal of Clinical Dermatology” Topical therapies show promise for hair loss and acne treatment with minimal side effects.
5 citations
,
April 2021 in “International Journal of Homoeopathic Sciences” Homeopathy improved Acne Keloidalis Nuchae in a 14-year-old.
5 citations
,
December 2014 in “Medicine and Pharmacy Reports” Ciproterone acetate improves hair regrowth and acne in most female patients.
5 citations
,
October 2014 in “Gynecological Endocrinology” Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.
3 citations
,
August 2019 in “Journal of The American Academy of Dermatology” Higher doses of spironolactone may improve acne in PCOS patients, but side effects are a concern.
3 citations
,
January 2018 in “Postępy Dermatologii i Alergologii” Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.
2 citations
,
July 2011 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Eating nuts, chocolate candy, and red tea might worsen acne, while eating more fresh vegetables could reduce it.
1 citations
,
November 2011 in “Open access journal of contraception” Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.
June 2026 in “Journal of Pakistan Association of Dermatologists” A study of 95 medical students at Universitas Sumatera Utara found a significant correlation between triglyceride levels and acne vulgaris severity, with higher triglyceride levels linked to more severe acne (P-value of 0.007). However, no significant relationship was observed between Body Mass Index (BMI) and acne severity. These findings suggest that triglycerides may be a modifiable factor in acne treatment, highlighting the need for further research to explore the role of lipid metabolism in acne development.
February 2026 in “International Journal of Web of Multidisciplinary Studies” Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
January 2026 in “Frontiers in Natural Products” Combining shikimic acid and Prunus mume extract may effectively treat acne naturally.