research The evolution of primary multimodality treatment in resectable breast cancer
Multimodal primary treatment improves survival in premenopausal breast cancer patients and is also beneficial for postmenopausal women.
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research The Hair Follicle as a Dynamic Miniorgan
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Defective trophoblast function in mice with a targeted mutation of Ets2
Ets2 gene is crucial for placental development in mice.
research Bioengineering skin using mechanisms of regeneration and repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
research Alopecia Areata: A tissue specific autoimmune disease of the hair follicle
Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
research Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation
Sulforaphane from broccoli can help protect skin from sun damage.
research Fetal Alcohol Syndrome: Current Status of Pathogenesis
The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
research Quality of Life, Burden of Disease, Co-morbidities, and Systemic Effects in Vitiligo Patients
Vitiligo affects overall health and self-esteem, needing more research and awareness.
research Expression patterns of three estrogen receptor genes during zebrafish (Danio rerio) development: evidence for high expression in neuromasts
The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
research Skin aging: are adipocytes the next target?
Targeting dermal adipocytes may help combat skin aging.
research External light activates hair follicle stem cells through eyes via an ipRGC–SCN–sympathetic neural pathway
Light can turn on hair growth cells through a nerve path starting in the eyes.
research Functional enhancement strategies for immunomodulation of mesenchymal stem cells and their therapeutic application
New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
research Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
research What controls hair follicle cycling?
The control system for hair growth cycles is not well understood and needs more research.
research Mechanisms and cell lineages in lymphatic vascular development
Lymphatic vessels develop from various cell types and mechanisms, not just veins.
research Increased levels of prostaglandin-like material in the canine blood during arterial hypotension produced by hydralazine, dihydralazine and minoxidil
These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Antidepressants have Anti-inflammatory Effects that may be Relevant to Dermatology: A Systematic Review
Antidepressants might help with skin inflammation and improve conditions like psoriasis and eczema.
research Novel inhibitors of 5α-reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Severe steroid-dependent idiopathic angioedema with response to rituximab
A woman with severe angioedema improved significantly after treatment with rituximab.
research Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle
Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
research The effects of extended photoperiod and warmth on hair growth in ponies and horses at different times of year
Timing of light therapy affects horse coat growth, with photoperiod being crucial.
research Dermatologic Signs and Symptoms of Substance Abuse
Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.
research Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss
Black raspberry extract may help with hair growth, skin whitening, and weight loss.
research Regeneration of hair and other skin appendages: A microenvironment‐centric view
The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
research Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha-ras genotype
Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
research Protective effects of finasteride on the pulmonary immune response in a combined model of trauma-hemorrhage and polymicrobial sepsis in mice
Finasteride helps reduce lung inflammation and damage after trauma and infection.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
research Finasteride administration potentiates the disruption of prepulse inhibition induced by forced swim stress
Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.