research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
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research Sulfatase inhibitors: a patent review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
research The non-neuronal and nonmuscular effects of botulinum toxin: an opportunity for a deadly molecule to treat disease in the skin and beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research Hair Bundle Defects and Loss of Function in the Vestibular End Organs of Mice Lacking the Receptor-Like Inositol Lipid Phosphatase PTPRQ
Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.
research Effects of autologous platelet‑rich plasma injections on facial skin rejuvenation
PRP injections improve facial skin by reducing wrinkles and pores.
research Recently Identified Forms of Epidermolysis Bullosa
Three new types of a skin blistering disease were found, caused by specific gene mutations.
research Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit (Oryctolagus cuniculus) Hair Follicle Cycle by RNA Sequencing
Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.
research The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells
The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes
Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
research Pathogenesis and treatment options for chemotherapy‐induced alopecia: a systematic review
Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
research Dermal and Transdermal Drug Delivery through Vesicles and Particles: Preparation and Applications
Transdermal drug delivery systems are effective and promising for future use.
research Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing
CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.
research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome
Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
research Use of extracellular matrix hydrogel from human placenta to restore hair-inductive potential of dermal papilla cells
Human placenta hydrogel helps restore cells needed for hair growth.
research Experimental and Clinical Pharmacology ofZiziphus jujubaMills
Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
research Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold
The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
research β-Catenin Inactivation Is a Pre-Requisite for Chick Retina Regeneration
Inactivating β-catenin is essential for chick retina regeneration.
research Role of stem/progenitor cells in reparative disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research MicroRNA in skin diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Development, formulation, and characterization of an adapalene-loaded solid lipid microparticle dispersion for follicular penetration
Researchers created a skin treatment that could effectively deliver medication into hair follicles.
research The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis
Blocking the NOTCH pathway can prevent fibrosis in systemic sclerosis.
research Differential expression and functionality of ATP-binding cassette transporters in the human hair follicle
Certain transporters are found in human hair follicles and may affect hair growth and loss.
research Epidermal keratinocyte stem cells: their maintenance and regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research The role of lysophosphatidic acid in the physiology and pathology of the skin
Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization
FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing
KLF4 is important for maintaining skin stem cells and helps heal wounds.
research Roles of steroid sulfatase in brain and other tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
research INTERFERONS IN DERMATOLOGY
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.