research Transcriptional profiling of putative human epithelial stem cells
Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
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450-480 / 1000+ resultsresearch Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity
Type VII collagen absence helps skin development by allowing tissue remodeling.
research Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis
Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
research Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
Myc activation reduces skin stem cells by affecting cell adhesion.
research Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells.
Desmocollin 1 and 3 have distinct patterns in human tissues, with Dsc1 in specific skin and hair layers and Dsc3 in various epithelial layers.
research Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes
BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.
research Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells
Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
research Keratinocyte-Specific Onset of Serine Protease BSSP Expression in Experimental Carcinogenesis
BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.
research NF-κB Activity Is Required for Anagen Maintenance in Human Hair Follicles In Vitro
NF-κB activity is crucial for keeping hair in the growth phase.
research Depletion of Gsdma1/2/3 alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway
Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.
research Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Hair follicle stem cells can form both hair follicles and skin.
research Characterization and isolation of stem cell-enriched human hair follicle bulge cells
Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
research Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors
Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
research Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation
Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
research Biphasic Regulation of HMG-CoA Reductase Expression and Activity during Wound Healing and Its Functional Role in the Control of Keratinocyte Angiogenic and Proliferative Responses
HMG-CoA reductase is crucial for skin wound healing by regulating keratinocyte growth and blood vessel formation.
research Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing
Dock5 is important for skin healing and could help treat diabetic wounds.
research PPAR‐γ signalling as a key mediator of human hair follicle physiology and pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
research Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling
A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.
research Ex Vivo Assessment of Heat and Humidity Effects on Human Skin and Potential Protection by Kombucha Tea Extract
Kombucha tea extract may protect skin from damage in hot and humid conditions.
research Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter
The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
research Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation
The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
research Expansion of Hair Follicle Stem Cells Sticking to Isolated Sebaceous Glands to Generate in Vivo Epidermal Structures
Sebaceous glands can help harvest hair follicle stem cells to regenerate skin and hair.
research Emerging Trends and Focus in Human Skin Microbiome Over the Last Decade: A Bibliometric Analysis and Literature Review
Research on the human skin microbiome has grown, focusing on skin health and diseases, with more studies needed on antibiotic resistance and AI applications.
research Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations
Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets.
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin
Dermal papilla cells help skin stem cells grow into hair.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Monoterpenoid Loliolide Regulates Hair Follicle Inductivity of Human Dermal Papilla Cells by Activating the Akt/ ¥-Catenin Signaling Pathway
Loliolide can boost hair growth by activating specific cell pathways.
research POLEVAN®—A Multifunctional Natural Hair Ingredient, as Determined by In-Vitro and Human Studies
POLEVAN® improves hair shine, moisturizes the scalp, and maintains foam quality in shampoos.