research The development of an in vitro human hair follicle organoid with a complexity similar to that in vivo
Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
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research Perspectives of Alopecia behind the Regulation of Foxn1 Gene Exposes the Human Nude Phenotype
The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
research Human dermal stem cells differentiate into functional epidermal melanocytes
Human dermal stem cells can become functional skin pigment cells.
research Current Protocols: Alopecia Areata Mouse Models for Drug Efficacy and Mechanism Studies
The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.
research Putting the Human Hair Follicle Cycle on the Map
The research created a model to understand human hair growth cycle, which can help diagnose and treat hair growth disorders and test potential hair growth drugs.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment
SM04755 may be an effective topical treatment for psoriasis.
research Pathobiology of chemotherapy-induced hair loss
Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
research Alopecia Areata
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research Next-Gen Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Transdermal Permeation of Drugs in Various Animal Species
Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
research Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
research Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles
Nanoplastics can penetrate skin cells, triggering inflammation and immune responses.
research Hair Growth-Promoting Effect of Hydrangea serrata (Thunb.) Ser. Extract and Its Active Component Hydrangenol: In Vitro and In Vivo Study
Hydrangea serrata extract may promote hair growth and improve hair health.
research Scalp condition improvement with botanical extracts possessing chemical and physical antioxidant activity
Botanical extracts can improve scalp health by reducing oxidative stress.
research Novel delivery strategy: finasteride-loaded solid lipid nanoparticles for improved androgenetic alopecia therapy
The new delivery method for finasteride using nanoparticles may improve hair growth without skin issues.
research Lidocaine-Loaded Solid Lipid Microparticles (SLMPs) Produced from Gas-Saturated Solutions for Wound Applications
Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.
research 742 Augmentation of HGF signaling: Potential for enhancing hair follicle neogenesis and development in bioengineered skin
Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
research Does prolactin play a role in skin biology and pathology?
Prolactin may be important for skin growth and immune function.
research Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies
Animal models have helped understand hair loss from alopecia areata and find new treatments.
research A neuroendocrinological perspective on human hair follicle pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
research Hairless is a nuclear receptor corepressor essential for skin function
Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
research The empowering influence of air-liquid interface culture on skin organoid hair follicle development
Air-liquid interface culture improves hair follicle development in skin organoids.
research T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
research Mimicking fat grafting of fibrotic scars using 3D‐organotypic skin cultures
Fat grafting reduces scar fibrosis but may slow skin healing.
research Targeting the Hippo/YAP /TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.