August 2024 in “Current Protocols” The C3H/HeJ mouse model is useful for studying and testing treatments for alopecia areata.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
32 citations
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August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” ARQ-234, a protein designed to treat atopic dermatitis, shows increased effectiveness in early testing.
59 citations
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September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
12 citations
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September 2024 in “JID Innovations” Skin-on-a-chip devices better mimic human skin for research.
79 citations
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January 2019 in “International Journal of Molecular Sciences” Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.
53 citations
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June 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Animal models help study psoriasis but have limitations and don't fully mimic the human disease.
13 citations
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March 2024 in “Cell Transplantation” Engineered skin tissue is a promising tool for safer cosmetic testing.
November 2025 in “Advanced Healthcare Materials” Bioprinting is improving skin models for better testing of skin diseases without using animals.
December 2024 in “Medical Review” Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
September 2015 in “Fluids and Barriers of the CNS” Three skull models were found most useful for testing hydrocephalus valve programming.
12 citations
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October 1988 in “Clinics in dermatology” The mouse model could be useful for baldness research and testing treatments like testosterone, cyproterone acetate, and minoxidil.
October 2021 in “Journal of Investigative Dermatology” The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
In vitro methods are crucial for developing effective and humane cosmetic ingredients.
239 citations
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December 2013 in “Scientific Reports” A new method quickly creates controllable cell clusters for tissue engineering and drug testing.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
25 citations
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March 2004 in “Regulatory Toxicology and Pharmacology” Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
38 citations
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July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
2 citations
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February 2025 in “Advances in Cosmetic Surgery” Exosome therapies could help with skin and hair issues, but more testing is needed.
1 citations
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April 2024 in “Pathogens” A pet ferret had a serious infection from Mycobacterium xenopi, which can spread to humans.
1 citations
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March 2024 in “Brain Imaging and Stimulation” A low-cost, 3D-printed light therapy device is safe and effective but needs more testing before use on people.
June 2025 in “Mağallaẗ ʻulūm al-rāfidayn” New pyrazole derivatives may help treat hair loss, but more testing is needed.
November 2020 in “Journal of Bioengineering and Technology Apllied for Health” COVID-19 affects multiple body systems and complicates treatment; accurate testing is crucial.
Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.
June 2006 in “Experimental dermatology” The document concludes that while finding animal models for the skin disease Hidradenitis suppurativa is challenging, certain mouse mutations may provide useful insights for research and drug testing.
14 citations
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November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
June 2023 in “Frontiers in Cardiovascular Medicine” Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
37 citations
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November 2007 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Black hair is fragile due to hair care practices, not structural differences.
31 citations
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April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.