188 citations
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June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
17 citations
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July 2024 in “Frontiers in Oncology” New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
45 citations
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July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
8 citations
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September 2023 in “International Journal of Nanomedicine” A new lab-grown lung model helps study adenoviruses and test antiviral drugs.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
27 citations
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July 2013 in “Journal of Investigative Dermatology” Revertant cell therapy shows promise for treating type XVII collagen deficiency, but better cell selection methods are needed.
6 citations
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November 2018 in “American journal of transplantation” UV light helped human hair transplants survive in mice without broad immunosuppression.
3 citations
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April 2023 in “Cytotechnology”
19 citations
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December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
12 citations
,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
January 2026 in “Journal of Investigative Dermatology” Special cells can help regrow hair in alopecia areata.
25 citations
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June 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” VDR regulation varies by tissue and is crucial for its biological functions.
17 citations
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
November 2023 in “Frontiers in Medicine” The method effectively mimics shaving damage on skin for testing skincare products.
March 2017 in “Fundamental & Clinical Pharmacology” The model and estimator can predict drug exposure in kidney transplant patients well.
March 2025 in “Nature Communications” NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
January 2026 in “Frontiers in Drug Discovery” Transforming skin disease treatment requires new strategies, better drug models, and patient-focused research.
39 citations
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March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
26 citations
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June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
6 citations
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July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
27 citations
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March 2019 in “PLoS ONE” Thyroxine (T4) may help heal skin wounds by promoting new skin and blood vessel growth.
April 2026 in “Signal Transduction and Targeted Therapy” Balancing testosterone may reduce COVID-19 severity.
11 citations
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February 2022 in “Scientific Reports” CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
51 citations
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August 2013 in “Journal of Investigative Dermatology” Human skin cells can create new hair follicles when transplanted into mice.
106 citations
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March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
94 citations
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
60 citations
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
57 citations
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February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
47 citations
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May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
32 citations
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March 2021 in “Journal of endocrinological investigation” Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.