research Phosphatidylinositol 3-Kinase/Akt-Dependent and -Independent Protection Against Apoptosis in Normal Human Melanocytes
Normal human melanocytes can avoid cell death through multiple pathways.
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330-360 / 1000+ resultsresearch Scalp Melanoma: A High-Risk Subset of Cutaneous Head and Neck Melanomas with Distinctive Clinicopathological Features
Scalp melanomas are more dangerous and likely to recur or cause death than other head and neck melanomas.
research Chemically Induced Depigmentation of Skin and Hair
Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
research Lipid‐mediated signalling and melanocyte function
A sphingolipid from human placenta may help treat vitiligo by activating melanocyte stem cells.
research Epidermal cells: methods and protocols
research External light activates hair follicle stem cells through eyes via an ipRGC–SCN–sympathetic neural pathway
Light can turn on hair growth cells through a nerve path starting in the eyes.
research Herbal insights into melanin synthesis: Enhancing hair health naturally
Melanin is important for hair color, health, and UV protection.
research Expression patterns of MITF during human cutaneous embryogenesis: evidence for bulge epithelial expression and persistence of dermal melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Identification of ultraviolet B radiation-induced microRNAs in normal human dermal papilla cells
UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
research Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis
RXRα is crucial for hair growth and skin cell function.
research The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted
The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
research Repurposing functional human hair melanosomes as a sunscreen product
Human hair melanosomes can be used to create effective, eco-friendly sunscreen.
research Multifunctional Merkel cells: Their roles in electromagnetic reception, finger-print formation, Reiki, epigenetic inheritance and hair form
Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.
research Decision letter: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
Moles may stop growing due to cell cooperation, not just because of individual cell aging.
research A Comprehensive Review on Skin Pigmentation-Types, Causes, and Treatment
Skin pigmentation varies due to genetics, UV exposure, and medications, with treatments available but requiring medical advice.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
research BMP4 regulates differentiation of nestin-positive stem cells into melanocytes
BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
research A case of systemic mastocytosis - an ultrastructural and immunohistochemical study of the dermal mast cells in relation to activation of the epidermal melanin unit
Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.
research 463 Spatial transcriptomics reveals an inflammatory profile in photoexposed light skin, which is absent in dark skin
Light skin shows more inflammation from sun exposure than dark skin.
research Neuropilin 2 expression and function in melanocytes and melanoma
Neuropilin 2 may be a biomarker for melanoma and affects melanocyte behavior.
research BJD Editor's Choice
Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.
research 647 NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity in human melanoma
NLRP1 helps melanoma tumors grow by boosting inflammasome activation and reducing caspase-3 activity.
research Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche
Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B1
Synthetic hormone treatment reduces melanin and hair growth in rats.
research Colourless side of the nude mutation: Foxn1 and hair pigmentation
Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
research Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled
Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
research Sox2 in the dermal papilla regulates hair follicle pigmentation
Sox2 controls hair color by affecting pigment production in hair follicles.
research A pair of transmembrane receptors essential for the retention and pigmentation of hair
Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
research Synergistic delivery of ginseng exosomes and biomimetic melanosomes via temporally controlled hydrogel microneedles restrain the pathologic triad of vitiligo
A new microneedle treatment can effectively repigment skin in vitiligo.
research Culture of amelanotic melanocytes derived from human fetal hair follicles
Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.