21 citations
,
July 2022 in “Orphanet journal of rare diseases” New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
19 citations
,
August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
19 citations
,
September 2006 in “Journal of Neurophysiology” Neurosteroids help balance brain signals when certain inhibitions are reduced.
18 citations
,
February 2025 in “Macromolecular Rapid Communications” Thermo-responsive polymers in nanoparticles enable targeted drug delivery and advanced therapies by releasing drugs at specific temperatures.
18 citations
,
July 2024 in “Frontiers in Immunology” Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
18 citations
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October 2022 in “Biomedicines” Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
17 citations
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July 2024 in “Advanced Intelligent Systems” Human-robot interaction becomes simpler as robots achieve full autonomy in surgery.
17 citations
,
May 2023 in “Pharmaceutics” Microneedles can precisely deliver cancer treatments with fewer side effects.
17 citations
,
February 2023 in “Cosmetics” 3D printed hollow microneedles could effectively treat skin wrinkles with fewer side effects.
17 citations
,
March 2012 in “Journal of biological chemistry/The Journal of biological chemistry” Hairless protein affects hair follicle structure by regulating the Dlx3 gene.
16 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
16 citations
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March 2021 in “EvoDevo” Different species use the same genes for tooth regeneration.
15 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
15 citations
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March 2021 in “Journal of Nanobiotechnology” A new method was developed to grow and maintain human hair follicle stem cells for hair reconstruction.
15 citations
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June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
15 citations
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March 2015 in “PloS one” Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
15 citations
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March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
14 citations
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November 2024 in “International Journal of Molecular Sciences” YAP and TAZ proteins control skin cell growth and repair.
14 citations
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February 2024 in “Pharmaceutics” We need to study how dissolving microneedles behave in the body to use them for medicine.
14 citations
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September 2023 in “Foods” Microfluidics can create precise, efficient delivery systems for food and cosmetics, but scaling up is challenging.
14 citations
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November 2022 in “Development” Controlling transposable elements is crucial for successful tissue regeneration.
13 citations
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December 2021 in “Molecules” Inorganic nanomaterials can improve brain disease imaging by being more precise and faster than traditional methods.
12 citations
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August 2022 in “Biochemical Journal” Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
12 citations
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October 2021 in “Cells” Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
12 citations
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January 2009 in “Stembook” Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
11 citations
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July 2024 in “Biomimetics” Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.
11 citations
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November 2021 in “JBMR plus” The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.
11 citations
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October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
11 citations
,
March 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
10 citations
,
March 2024 in “Endocrine Reviews” Significant progress was made in understanding androgen excess disorders, but much is still unknown.