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research Cortisol Enhances the Expression of mac25/Insulin-Like Growth Factor-Binding Protein-Related Protein-1 in Cultured Osteoblasts**This work was supported by NIDDK Grant DK-45227 and a scholarship (to R.C.P.) from Fundacao Coordenacao de Aperfeicoa mento de Pessoal de Nivel Superior (CAPES), Universidade de Sao Paulo (Sao Paulo, Brazil).

43 citations , January 1999 in “Endocrinology”

Cortisol increases a specific protein in bone cells, which may help explain its negative effects on bone.

research Integrated analysis of coding genes and non-coding RNAs during hair follicle cycle of cashmere goat (Capra hircus)

129 citations , October 2017 in “BMC Genomics”

The study improved understanding of gene roles in cashmere goat hair growth, aiding future cashmere production.

research Theoretical investigation on the construction of hair follicle membranes and the transdermal drug delivery mechanisms of JAK inhibitors via distinct pathways

February 2026 in “Colloids and Surfaces A Physicochemical and Engineering Aspects”

JAK inhibitors can enter the skin through hair follicles using a unique pathway.

research Identification of differentially expressed genes HSPC016 in dermal papilla cells with aggregative behavior

5 citations , August 2005 in “Archives of Dermatological Research”

HSPC016 gene is important for hair growth.

research TLR3 signaling modulates immunomodulatory property of human periodontal ligament stem cells.

January 2018

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

research scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

July 2025

Dual TCR Treg cells are common in mouse tissues and vary by location.

research Expression analysis of KAP9.2 and Hoxc13 genes during different cashmere growth stages by qRT-PCR method

9 citations , June 2014 in “Molecular biology reports”

KAP9.2 and Hoxc13 genes are important for cashmere growth and vary in activity during different stages.

research LB793 A phase 1, open-Label, single ascending dose study in healthy subjects of the safety, tolerability and pharmacokinetics of ASLAN004, a novel IgG anti-IL-13 receptor alpha 1 Inhibitor

1 citations , August 2021 in “Journal of Investigative Dermatology”

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

research Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide

130 citations , January 2000 in “Nature biotechnology”

research Localization and Regulation of Expression of the FAR-17A Gene in the Hamster Flank Organs

16 citations , July 1996 in “Journal of Investigative Dermatology”

research Analysis of histology and long noncoding RNAs involved in the rabbit hair follicle density using RNA sequencing

January 2021 in “Research Square (Research Square)”

Long noncoding RNAs may help understand rabbit hair follicle density.

Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice

research Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice

7 citations , February 2023 in “Inflammation and Regeneration”

The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.

research Integrated Transcriptome Analysis of lncRNA, miRNA, and mRNA Reveals key Regulatory Modules for Polycystic Ovary Syndrome

2 citations , October 2024 in “Phenomics”

research Androgen receptor inhibits the hair follicle induction potential of dermal papilla cells by binding with Tcf4 at the A574 binding site

4 citations , May 2022 in “Genes & Diseases”

research URB expression in human dermal papilla cells

7 citations , July 2005 in “Journal of Dermatological Science”

The gene URB is more active in human hair growth cells and responds to a hair-related hormone.

research 616 Endoplasmic reticulum stress upregulates NKG2D ligands in the hair follicle

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.

research Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex

124 citations , April 2000 in “Nature biotechnology”

research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt^WT mice

8 citations , September 2013 in “Molecular carcinogenesis”

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

research RETRACTED: Interleukin‐33 links asthma to alopecia areata: Mendelian randomization and mediation analysis

4 citations , August 2024 in “Skin Research and Technology”

research S3886 Concurrent Management of Crohn's Ileitis and Alopecia Universalis With Upadacitinib

October 2024 in “The American Journal of Gastroenterology”

Upadacitinib improved both Crohn's ileitis and alopecia universalis in a patient.

research Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression

14 citations , April 2016 in “PloS one”

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

research 865 Single-cell protein activity inference analysis of full-thickness skin uncovers novel pathways and a rare Arg1+ macrophage population in AA

July 2022 in “Journal of Investigative Dermatology”

Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.

research Characterization and expression analysis of the hair keratin associated protein KAP26.1

50 citations , July 2008 in “British Journal of Dermatology”

Elevated Mammalian Target of Rapamycin Gene Expression in Acne Vulgaris Patients

research Elevated Mammalian Target of Rapamycin (mTOR) Gene Expression in Acne Vulgaris patients

January 2023 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal”

Acne patients have higher mTOR gene expression.

research Latent transforming growth factor beta-binding protein 1 (LTBP1): roles as a multifunctional extracellular matrix regulator in human disease. From molecular mechanisms to clinical translation prospects

March 2026 in “Folia Histochemica et Cytobiologica”

LTBP1 is a key regulator in diseases and a potential target for new treatments.

research 1349 Stimulation of hair follicle stem cell proliferation through an IL-1α dependent activation of γδT-cells

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain immune cells, when activated by specific signals, can encourage hair growth.

research Isolation and Characterization of a Novel Hair Follicle–Specific Gene, Hacl-1

25 citations , May 1994 in “Journal of Investigative Dermatology”

Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.

Transcriptome Sequencing Reveals Expression Profiles of lncRNAs and mRNAs in Goat Skin Tissues with Different Wool Coat Types

research Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats

April 2025

Different wool coat types in goats are linked to specific gene expressions, which could improve cashmere quality.

research Mammalian target of rapamycin complex 1 (mTORC1) may modulate the timing of anagen entry in mouse hair follicles

28 citations , November 2012 in “Experimental dermatology”

A protein complex called mTORC1 likely affects when hair growth starts in mice.

research Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits

42 citations , January 2017 in “Genes”

The gene KAP22-1 affects wool yield and fiber shape in sheep.

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