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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

PD‐L1 and PD‐L2 may not effectively control immune activation in alopecia areata.

A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.

Notch1 helps skin heal by attracting cells that aid repair.

Higher interleukin-15 levels are linked to more severe alopecia areata, but not to age or gender.

Hair follicle cells help protect against immune attacks by regulating T-cell activity.

Lower GATA3 levels in mice help hair regrow by changing certain immune cells.

OR101 may effectively treat atopic dermatitis and similar skin conditions.

Igf1r helps regulate hair growth cycles.

HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.

The PIP5K1A gene helps cashmere growth in goats by promoting cell proliferation, and melatonin boosts its expression.

The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.

IL-17 inhibitors are more effective than methotrexate in preventing psoriatic arthritis in psoriasis patients.

Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.

Plasmacytoid dendritic cells, which overproduce IFN-α, may play a crucial role in starting alopecia areata, an autoimmune disease causing hair loss.

MCPIP1 in myeloid cells is important for skin cancer development and healthy hair growth.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Laminin-511 is essential for proper melanocyte movement and development in mice.

Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

A new mutation in the LIPH gene was found to cause a rare hair disorder in a Japanese boy.

Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.

Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

IL-27 can prevent hair loss in alopecia areata.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Baricitinib might help treat hair loss in lupus patients, but more research is needed.